PDF(Pubmed)
Abstract：
BACKGROUND: This study investigated the impacts of exercise on irisin and fibroblast growth factor 21 (FGF-21) expression, as well as triiodothyronine (T3 ) and free fatty acid (FFA) levels in elderly women.
METHODS: Thirty women aged 65 to 70 years (10 per group) were randomly assigned to aquatic exercise, land exercise, and control groups. The aquatic and land groups engaged in 3 exercise sessions per week (60 min/session) for 16 weeks. The intensity was progressively increased every 4 weeks.
RESULTS: Irisin and FGF-21 levels significantly increased in the aquatic exercise group. In the posttest, the aquatic exercise group had the highest irisin levels. Significant findings were observed for irisin and FGF-21 for the main effect between aquatic and band exercise groups (p<0.05 for both), the main effect between measurement times (p<0.01 and p<0.001, respectively), and the interaction effect (p<0.05 and p<0.001, respectively). The irisin level was significantly higher in the aquatic than in the land group 30 minutes after the last session (p<0.05). In both exercise groups, T3 levels were significantly higher 30 minutes after the final session (p<0.05) than before the program. The FFA level was significantly higher in the aquatic exercise group than the others. In the aquatic group, FFA levels were significantly higher 30 minutes after both the first (p<0.01) and the last (p<0.001) session compared to pre-program values.
CONCLUSIONS: Differences in exercise type and environment can promote fat metabolism by stimulating hormonal changes that induce brown fat activity and browning.
METHODS: Thirty women aged 65 to 70 years (10 per group) were randomly assigned to aquatic exercise, land exercise, and control groups. The aquatic and land groups engaged in 3 exercise sessions per week (60 min/session) for 16 weeks. The intensity was progressively increased every 4 weeks.
RESULTS: Irisin and FGF-21 levels significantly increased in the aquatic exercise group. In the posttest, the aquatic exercise group had the highest irisin levels. Significant findings were observed for irisin and FGF-21 for the main effect between aquatic and band exercise groups (p<0.05 for both), the main effect between measurement times (p<0.01 and p<0.001, respectively), and the interaction effect (p<0.05 and p<0.001, respectively). The irisin level was significantly higher in the aquatic than in the land group 30 minutes after the last session (p<0.05). In both exercise groups, T3 levels were significantly higher 30 minutes after the final session (p<0.05) than before the program. The FFA level was significantly higher in the aquatic exercise group than the others. In the aquatic group, FFA levels were significantly higher 30 minutes after both the first (p<0.01) and the last (p<0.001) session compared to pre-program values.
CONCLUSIONS: Differences in exercise type and environment can promote fat metabolism by stimulating hormonal changes that induce brown fat activity and browning.
摘要：
背景：这项研究调查了运动对irisin和成纤维细胞生长因子21（FGF-21）表达的影响，以及老年妇女的三碘甲状腺原氨酸（T3）和游离脂肪酸（FFA）水平。
方法：30名年龄在65至70岁（每组10名）的女性被随机分配到水中运动，土地演习,和对照组。水生和陆地组每周进行3次锻炼（60分钟/次），持续16周。强度每4周逐渐增加。
结果：在水上运动组中，Irisin和FGF-21水平显著升高。在后测中，水上运动组的irisin水平最高。观察到irisin和FGF-21在水上运动组和乐队运动组之间的主要作用的显着发现（p<0.05），测量次数之间的主要影响（分别为p<0.01和p<0.001），和交互效应(分别为p<0.05和p<0.001)。末次试验后30分钟，水生组的irisin水平明显高于陆地组（p<0.05）。在两个锻炼组中，T3水平在最后阶段后30分钟显著高于程序前(p<0.05)。水中运动组的FFA水平明显高于其他组。在水生群体中，与程序前的值相比,FFA水平在第一次(p<0.01)和最后一次(p<0.001)会话后30分钟显著更高。
结论：运动类型和环境的差异可以通过刺激激素变化来促进脂肪代谢，从而诱导棕色脂肪活动和褐变。
方法：30名年龄在65至70岁（每组10名）的女性被随机分配到水中运动，土地演习,和对照组。水生和陆地组每周进行3次锻炼（60分钟/次），持续16周。强度每4周逐渐增加。
结果：在水上运动组中，Irisin和FGF-21水平显著升高。在后测中，水上运动组的irisin水平最高。观察到irisin和FGF-21在水上运动组和乐队运动组之间的主要作用的显着发现（p<0.05），测量次数之间的主要影响（分别为p<0.01和p<0.001），和交互效应(分别为p<0.05和p<0.001)。末次试验后30分钟，水生组的irisin水平明显高于陆地组（p<0.05）。在两个锻炼组中，T3水平在最后阶段后30分钟显著高于程序前(p<0.05)。水中运动组的FFA水平明显高于其他组。在水生群体中，与程序前的值相比,FFA水平在第一次(p<0.01)和最后一次(p<0.001)会话后30分钟显著更高。
结论：运动类型和环境的差异可以通过刺激激素变化来促进脂肪代谢，从而诱导棕色脂肪活动和褐变。
