METHODS: A prospective study was conducted across 11 districts of Delhi, India, among individuals who had recovered from COVID-19. Study participants were enrolled, and then returned for post-recovery follow-up at 3 months and 6 months interval.
RESULTS: The mean age of study participants was 42.07 years, with a standard deviation of 14.89 years. The majority of the participants (79.7%) reported experiencing post-COVID-19 symptoms. The most common symptoms included joint pain (36.0%), persistent dry cough (35.7%), anxiety (28.4%), and shortness of breath (27.1%). Other symptoms were persistent fatigue (21.6%), persistent headache (20.0%), forgetfulness (19.7%), and limb weakness (18.6%). The longest duration of symptom was observed to be anxiety (138.75±54.14 days), followed by fatigue (137.57±48.33 days), shortness of breath (131.89±60.21 days), and joint pain/swelling (131.59±58.76 days). At the first follow-up visit, 2.2% of participants presented with abnormal electrocardiogram readings, but no abnormalities were noticed during the second follow-up. Additionally, 4.06% of participants exhibited abnormal chest X-ray findings at the first followup, which decreased to 2.16% by the second visit.
CONCLUSIONS: The most frequently reported post-COVID-19 symptoms were joint pain, dry cough, anxiety and shortness of breath. These clinical symptoms persisted for up to 6 months, with evidence of multi-system involvement. Consequently, findings highlighted the need for long-term follow-up during the post-COVID-19 period.
方法:在德里的11个地区进行了一项前瞻性研究,印度,在从COVID-19中康复的个体中。研究参与者被纳入,然后以3个月和6个月的间隔返回恢复后随访。
结果:研究参与者的平均年龄为42.07岁,标准差为14.89年。大多数参与者(79.7%)报告经历了COVID-19后症状。最常见的症状包括关节痛(36.0%),持续干咳(35.7%),焦虑(28.4%),呼吸急促(27.1%)。其他症状为持续性疲乏(21.6%),持续性头痛(20.0%),健忘(19.7%),和四肢无力(18.6%)。症状持续时间最长为焦虑(138.75±54.14天),其次是疲劳(137.57±48.33天),呼吸急促(131.89±60.21天),和关节痛/肿胀(131.59±58.76天)。在第一次后续访问中,2.2%的参与者表现出异常的心电图读数,但在第二次随访期间未发现异常.此外,4.06%的参与者在第一次随访时表现出异常的胸部X线检查结果,第二次访问时下降至2.16%。
结论:COVID-19后最常见的症状是关节痛,干咳,焦虑和呼吸急促。这些临床症状持续长达6个月,有多系统参与的证据。因此,研究结果强调了在COVID-19后期间进行长期随访的必要性。