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Abstract：
BACKGROUND: Post-coronavirus disease 2019 (COVID-19) symptoms were widely reported. However, data on post-COVID-19 conditions following infection with the Omicron variant remained scarce. This prospective study was conducted to understand the prevalence, patterns, and duration of symptoms in patients who had recovered from COVID-19.
METHODS: A prospective study was conducted across 11 districts of Delhi, India, among individuals who had recovered from COVID-19. Study participants were enrolled, and then returned for post-recovery follow-up at 3 months and 6 months interval.
RESULTS: The mean age of study participants was 42.07 years, with a standard deviation of 14.89 years. The majority of the participants (79.7%) reported experiencing post-COVID-19 symptoms. The most common symptoms included joint pain (36.0%), persistent dry cough (35.7%), anxiety (28.4%), and shortness of breath (27.1%). Other symptoms were persistent fatigue (21.6%), persistent headache (20.0%), forgetfulness (19.7%), and limb weakness (18.6%). The longest duration of symptom was observed to be anxiety (138.75±54.14 days), followed by fatigue (137.57±48.33 days), shortness of breath (131.89±60.21 days), and joint pain/swelling (131.59±58.76 days). At the first follow-up visit, 2.2% of participants presented with abnormal electrocardiogram readings, but no abnormalities were noticed during the second follow-up. Additionally, 4.06% of participants exhibited abnormal chest X-ray findings at the first followup, which decreased to 2.16% by the second visit.
CONCLUSIONS: The most frequently reported post-COVID-19 symptoms were joint pain, dry cough, anxiety and shortness of breath. These clinical symptoms persisted for up to 6 months, with evidence of multi-system involvement. Consequently, findings highlighted the need for long-term follow-up during the post-COVID-19 period.
METHODS: A prospective study was conducted across 11 districts of Delhi, India, among individuals who had recovered from COVID-19. Study participants were enrolled, and then returned for post-recovery follow-up at 3 months and 6 months interval.
RESULTS: The mean age of study participants was 42.07 years, with a standard deviation of 14.89 years. The majority of the participants (79.7%) reported experiencing post-COVID-19 symptoms. The most common symptoms included joint pain (36.0%), persistent dry cough (35.7%), anxiety (28.4%), and shortness of breath (27.1%). Other symptoms were persistent fatigue (21.6%), persistent headache (20.0%), forgetfulness (19.7%), and limb weakness (18.6%). The longest duration of symptom was observed to be anxiety (138.75±54.14 days), followed by fatigue (137.57±48.33 days), shortness of breath (131.89±60.21 days), and joint pain/swelling (131.59±58.76 days). At the first follow-up visit, 2.2% of participants presented with abnormal electrocardiogram readings, but no abnormalities were noticed during the second follow-up. Additionally, 4.06% of participants exhibited abnormal chest X-ray findings at the first followup, which decreased to 2.16% by the second visit.
CONCLUSIONS: The most frequently reported post-COVID-19 symptoms were joint pain, dry cough, anxiety and shortness of breath. These clinical symptoms persisted for up to 6 months, with evidence of multi-system involvement. Consequently, findings highlighted the need for long-term follow-up during the post-COVID-19 period.
摘要：
背景：2019年冠状病毒病后（COVID-19）症状被广泛报道。然而,Omicron变异体感染后COVID-19后疾病的数据仍然很少。这项前瞻性研究是为了了解患病率，模式,以及从COVID-19中康复的患者的症状持续时间。
方法：在德里的11个地区进行了一项前瞻性研究，印度,在从COVID-19中康复的个体中。研究参与者被纳入，然后以3个月和6个月的间隔返回恢复后随访。
结果：研究参与者的平均年龄为42.07岁，标准差为14.89年。大多数参与者（79.7%）报告经历了COVID-19后症状。最常见的症状包括关节痛（36.0％），持续干咳（35.7%），焦虑（28.4%），呼吸急促(27.1%)。其他症状为持续性疲乏(21.6%),持续性头痛（20.0%），健忘（19.7%），和四肢无力（18.6%）。症状持续时间最长为焦虑（138.75±54.14天），其次是疲劳（137.57±48.33天），呼吸急促（131.89±60.21天），和关节痛/肿胀（131.59±58.76天）。在第一次后续访问中，2.2%的参与者表现出异常的心电图读数，但在第二次随访期间未发现异常.此外,4.06%的参与者在第一次随访时表现出异常的胸部X线检查结果，第二次访问时下降至2.16%。
结论：COVID-19后最常见的症状是关节痛，干咳,焦虑和呼吸急促。这些临床症状持续长达6个月，有多系统参与的证据。因此,研究结果强调了在COVID-19后期间进行长期随访的必要性。
方法：在德里的11个地区进行了一项前瞻性研究，印度,在从COVID-19中康复的个体中。研究参与者被纳入，然后以3个月和6个月的间隔返回恢复后随访。
结果：研究参与者的平均年龄为42.07岁，标准差为14.89年。大多数参与者（79.7%）报告经历了COVID-19后症状。最常见的症状包括关节痛（36.0％），持续干咳（35.7%），焦虑（28.4%），呼吸急促(27.1%)。其他症状为持续性疲乏(21.6%),持续性头痛（20.0%），健忘（19.7%），和四肢无力（18.6%）。症状持续时间最长为焦虑（138.75±54.14天），其次是疲劳（137.57±48.33天），呼吸急促（131.89±60.21天），和关节痛/肿胀（131.59±58.76天）。在第一次后续访问中，2.2%的参与者表现出异常的心电图读数，但在第二次随访期间未发现异常.此外,4.06%的参与者在第一次随访时表现出异常的胸部X线检查结果，第二次访问时下降至2.16%。
结论：COVID-19后最常见的症状是关节痛，干咳,焦虑和呼吸急促。这些临床症状持续长达6个月，有多系统参与的证据。因此,研究结果强调了在COVID-19后期间进行长期随访的必要性。
