PDF(Pubmed)
Abstract：
Acrylic resins are widely used as the main components in removable orthodontic appliances. However, poor oral hygiene and maintenance of orthodontic appliances provide a suitable environment for the growth of pathogenic microorganisms. In this study, strontium-modified phosphate-based glass (Sr-PBG) was added to orthodontic acrylic resin at 0% (control), 3.75%, 7.5%, and 15% by weight to evaluate the surface and physicochemical properties of the novel material and its in vitro antifungal effect against Candida albicans (C. albicans). Surface microhardness and contact angle did not vary between the control and 3.75% Sr-PBG groups (p > 0.05), and the flexural strength was lower in the experimental groups than in the control group (p < 0.05), but no difference was found with Sr-PBG content (p > 0.05). All experimental groups showed an antifungal effect at 24 and 48 h compared to that in the control group (p < 0.05). This study demonstrated that 3.75% Sr-PBG exhibits antifungal effects against C. albicans along with suitable physicochemical properties, which may help to minimize the risk of adverse effects associated with harmful microbial living on removable orthodontic appliances and promote the use of various materials.
摘要：
丙烯酸树脂广泛用作可移除正畸矫治器的主要组分。然而,口腔卫生差和正畸矫治器的维护为病原微生物的生长提供了合适的环境。在这项研究中,锶改性磷酸盐基玻璃（Sr-PBG）以0％（对照）添加到正畸丙烯酸树脂中，3.75%,7.5%,和15重量％，以评估新型材料的表面和理化性质及其对白色念珠菌的体外抗真菌作用（C.albicans).表面显微硬度和接触角在对照组和3.75％Sr-PBG组之间没有变化（p>0.05），试验组抗弯强度低于对照组(p<0.05),但Sr-PBG含量无差异(p>0.05)。与对照组相比，所有实验组在24和48小时均显示出抗真菌作用（p<0.05）。这项研究表明，3.75％Sr-PBG对白色念珠菌具有抗真菌作用以及合适的理化性质，这可能有助于将与有害微生物生活在可移动正畸矫治器上相关的不利影响的风险降至最低，并促进各种材料的使用。
