Mesh : Humans Aorta, Abdominal / physiology Blood Flow Velocity / physiology Weightlessness Hemodynamics / physiology Iliac Artery Models, Cardiovascular Earth, Planet Weightlessness Simulation

来  源:   DOI:10.1038/s41598-024-66961-7   PDF(Pubmed)

Abstract:
Blood flow through the abdominal aorta and iliac arteries is a crucial area of research in hemodynamics and cardiovascular diseases. To get in to the problem, this study presents detailed analyses of blood flow through the abdominal aorta, together with left and right iliac arteries, under Earth gravity and weightless conditions, both at the rest stage, and during physical activity. The analysis were conducted using ANSYS Fluent software. The results indicate, that there is significantly less variation in blood flow velocity under weightless conditions, compared to measurement taken under Earth Gravity conditions. Study presents, that the maximum and minimum blood flow velocities decrease and increase, respectively, under weightless conditions. Our model for the left iliac artery revealed higher blood flow velocities during the peak of the systolic phase (systole) and lower velocities during the early diastolic phase (diastole). Furthermore, we analyzed the shear stress of the vessel wall and the mean shear stress over time. Additionally, the distribution of oscillatory shear rate, commonly used in hemodynamic analyses, was examined to assess the effects of blood flow on the blood vessels. Countermeasures to mitigate the negative effects of weightlessness on astronauts health are discussed, including exercises performed on the equipment aboard the space station. These exercises aim to maintain optimal blood flow, prevent the formation of atherosclerotic plaques, and reduce the risk of cardiovascular complications.
摘要:
通过腹主动脉和髂动脉的血流是血液动力学和心血管疾病研究的关键领域。为了解决这个问题,这项研究提供了通过腹主动脉的血流的详细分析,连同左右髂动脉,在地球重力和失重条件下,都在休息阶段,在身体活动期间。使用ANSYSFluent软件进行分析。结果表明,失重条件下血流速度的变化明显较小,与在地球重力条件下进行的测量相比。研究报告,最大和最小血流速度减少和增加,分别,在失重条件下。我们的左动脉模型显示,收缩期(收缩期)的峰值血流速度较高,而舒张早期(舒张期)的血流速度较低。此外,我们分析了血管壁的剪切应力和平均剪切应力随时间的变化。此外,振荡剪切速率的分布,常用于血液动力学分析,进行检查以评估血流对血管的影响。探讨了减轻失重对航天员健康的负面影响的对策,包括在空间站上的设备上进行的演习。这些练习旨在维持最佳的血液流动,防止动脉粥样硬化斑块的形成,并降低心血管并发症的风险。
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