Abstract：
The purpose of the study was to determine the antibiotic prescribing pattern of oral health practitioners before and during the Coronavirus disease 2019 (COVID-19) pandemic at Wits Oral Health Centre, South Africa. A retrospective, descriptive study was conducted using a systematic random sample of 698 records of patients who were prescribed antibiotics. The records were categorised into two groups: pre-COVID-19 and COVID-19 pandemic periods. For each group, data collected and analysed included variables such as patient demographics, prescriber discipline, medical history, dental condition, dental procedure, type of antibiotic, dose, frequency, and duration. Most patients in both the pre-COVID-19 and COVID-19 groups (70.3% and 73%, respectively) were healthy. The most common indication for prescribing antibiotics was a painful tooth (58.7%). Amoxycillin and metronidazole remain the antibiotics of choice for most dental conditions. More patients were treated with antibiotics only in the COVID-19 group than the pre-COVID-19 group (46.8% vs 33.7%). A significant proportion of the prescribed antibiotics were not indicated in both the pre-COVID-19 and COVID-19 groups (53.1% and 54.3%, respectively). The increased antibiotic usage during the COVID-19 period, in spite of the decrease in the number of patients consulted, underscores the need for more strategies to be implemented to strengthen antimicrobial resistance surveillance and stewardship initiatives.
摘要：
这项研究的目的是确定Wits口腔健康中心2019年冠状病毒病(COVID-19)大流行之前和期间口腔保健医生的抗生素处方模式，南非。回顾，描述性研究是使用698例抗生素处方患者的系统随机样本进行的.记录分为两组：COVID-19前和COVID-19大流行期。对于每个小组，收集和分析的数据包括变量，如患者人口统计，处方者纪律，病史,牙齿状况,牙科手术,抗生素的类型，剂量,频率,和持续时间。COVID-19和COVID-19组的大多数患者（70.3%和73%，分别)是健康的。开抗生素最常见的适应症是牙齿疼痛（58.7％）。阿莫西林和甲硝唑仍然是大多数牙科疾病的首选抗生素。COVID-19组仅接受抗生素治疗的患者多于COVID-19组(46.8%vs33.7%)。在COVID-19之前和COVID-19组中，有相当比例的处方抗生素没有被使用(53.1%和54.3%，分别)。COVID-19期间抗生素使用量的增加，尽管接受咨询的患者数量有所减少，强调需要实施更多战略以加强抗菌素耐药性监测和管理举措。
