Tepotinib 治疗患有晚期非小细胞肺癌的患者 , 患有 MET 第 14 外显子跳跃 , 同时进行肾衰竭的血液透析 : 病例报告。
关键词: End stage renal disease (ESRD) MET inhibitor Mesenchymal-epithelial transition factor Pharmacokinetics (PK) Severe renal impairment
Mesh : Humans Carcinoma, Non-Small-Cell Lung / drug therapy genetics complications pathology Lung Neoplasms / genetics drug therapy pathology complications Renal Dialysis Proto-Oncogene Proteins c-met / genetics Exons / genetics Pyrimidines / therapeutic use Male Renal Insufficiency / therapy Pyridines / therapeutic use Middle Aged Aged Antineoplastic Agents / therapeutic use Piperidines Pyridazines
来 源: DOI:10.1016/j.cllc.2024.05.008