METHODS: A randomized crossover clinical trial was realized in 3 sessions: in the first session a clinical history, anthropometric measurements and body composition analysis were performed; in sessions 2 and 3 the participants randomly consumed 240mL of coffee with 6mg/caffeine/kg of weight or 240mL of water along with a standardized breakfast. At fasting and every 30min after breakfast for the next 3h, appetite sensations and SSD were recorded using visual analog scales. Blood samples were taken at fasting, 30 and 180min after breakfast. Dietary intake was recorded in the rest of the intervention days.
RESULTS: In the coffee intervention there was an increased desire for sweet foods, higher fructose intake during the rest of the day, and higher triglyceride levels than with the water intervention. No differences were detected in ghrelin or cholecystokinin.
CONCLUSIONS: Coffee consumption may lead to higher triglycerides and higher intake of simple sugars, mainly fructose, through changes in the SSD.
BACKGROUND: https://clinicaltrials.gov/NCT05774119.
方法:在3个疗程中实现了一项随机交叉临床试验:在第一个疗程中,我们进行了人体测量和身体成分分析;在第2和第3阶段,参与者随机饮用240mL含6mg/kg咖啡因/kg体重的咖啡或240mL水以及标准早餐.在禁食和早餐后每30分钟,接下来的3小时,使用视觉模拟量表记录食欲感觉和SSD。在禁食时采集血样,早餐后30和180分钟。在其余的干预日记录饮食摄入量。
结果:在咖啡干预中,人们对甜食的渴望增加,在一天的剩余时间里摄入更多的果糖,甘油三酯水平高于水干预。没有检测到ghrelin或胆囊收缩素的差异。
结论:咖啡消费可能导致更高的甘油三酯和更高的单糖摄入量,主要是果糖,通过SSD的变化。
背景:https://clinicaltrials.gov/NCT05774119.