Abstract：
BACKGROUND: Melioidosis may occasionally be encountered in non-endemic areas and medical imaging is frequently used to identify and characterise sites of disease. The purpose of this study is to describe the spectrum of imaging findings encountered in melioidosis patients treated in the tertiary public hospitals of Perth, Western Australia, between 2002 and 2022.
METHODS: A database search and electronic medical record review was used to identify cases. Cases were included if they had Burkholderia pseudomallei isolated on culture and if they had at least one diagnostic imaging study performed at a Perth public tertiary hospital. The relevant imaging studies were reviewed, and imaging findings were recorded.
RESULTS: Thirty-six cases were identified. The most common disease manifestation was bacteraemia (72%, 26 cases), followed by pulmonary infection (58%, 21 cases), skin and soft tissue infection (22%, eight cases), prostate abscess (14%, five cases) and septic arthritis (6%, two cases). A previously unreported case of isolated melioid pleural effusion was identified, as was a case of reactivated chronic latent pulmonary melioidosis with an apparent delay of over 20 years between the onset of symptoms and the time of infection. In cases with pulmonary melioidosis, the major lung abnormalities on CT chest could be categorised into one of two distinct patterns: nodular-predominant (78%) or consolidation-predominant (22%).
CONCLUSIONS: Further research is required to assess the utility of the pattern-based categorisation of lung abnormalities on CT chest seen in the pulmonary melioidosis cases of this series.
METHODS: A database search and electronic medical record review was used to identify cases. Cases were included if they had Burkholderia pseudomallei isolated on culture and if they had at least one diagnostic imaging study performed at a Perth public tertiary hospital. The relevant imaging studies were reviewed, and imaging findings were recorded.
RESULTS: Thirty-six cases were identified. The most common disease manifestation was bacteraemia (72%, 26 cases), followed by pulmonary infection (58%, 21 cases), skin and soft tissue infection (22%, eight cases), prostate abscess (14%, five cases) and septic arthritis (6%, two cases). A previously unreported case of isolated melioid pleural effusion was identified, as was a case of reactivated chronic latent pulmonary melioidosis with an apparent delay of over 20 years between the onset of symptoms and the time of infection. In cases with pulmonary melioidosis, the major lung abnormalities on CT chest could be categorised into one of two distinct patterns: nodular-predominant (78%) or consolidation-predominant (22%).
CONCLUSIONS: Further research is required to assess the utility of the pattern-based categorisation of lung abnormalities on CT chest seen in the pulmonary melioidosis cases of this series.
摘要：
背景：非地方病区偶尔会遇到类鼻窦炎，医学成像经常用于识别和表征疾病部位。这项研究的目的是描述在珀斯三级公立医院接受治疗的类lioidosis患者中遇到的成像发现的频谱，西澳大利亚,从2002年到2022年。
方法：使用数据库搜索和电子病历审查来识别病例。如果他们在培养中分离出了假伯克霍尔德氏菌，并且在珀斯公立三级医院进行了至少一项诊断性影像学研究，则将其包括在内。回顾了相关的影像学研究，并记录影像学检查结果.
结果：确定了36例。最常见的疾病表现是菌血症（72%，26例)，其次是肺部感染(58%，21例)，皮肤和软组织感染(22%，八个案例)，前列腺脓肿（14%，5例）和化脓性关节炎（6％，两个案例)。确定了以前未报告的孤立性melioid胸腔积液病例，再激活的慢性潜伏性肺类骨病也是如此，在症状发作和感染时间之间明显延迟超过20年。在患有肺类骨病的病例中，CT胸部的主要肺部异常可以分为两种不同的模式之一：结节为主（78％）或合并为主（22％）。
结论：需要进一步的研究来评估在本系列肺类石症病例中看到的CT胸部基于模式的肺部异常分类的实用性。
方法：使用数据库搜索和电子病历审查来识别病例。如果他们在培养中分离出了假伯克霍尔德氏菌，并且在珀斯公立三级医院进行了至少一项诊断性影像学研究，则将其包括在内。回顾了相关的影像学研究，并记录影像学检查结果.
结果：确定了36例。最常见的疾病表现是菌血症（72%，26例)，其次是肺部感染(58%，21例)，皮肤和软组织感染(22%，八个案例)，前列腺脓肿（14%，5例）和化脓性关节炎（6％，两个案例)。确定了以前未报告的孤立性melioid胸腔积液病例，再激活的慢性潜伏性肺类骨病也是如此，在症状发作和感染时间之间明显延迟超过20年。在患有肺类骨病的病例中，CT胸部的主要肺部异常可以分为两种不同的模式之一：结节为主（78％）或合并为主（22％）。
结论：需要进一步的研究来评估在本系列肺类石症病例中看到的CT胸部基于模式的肺部异常分类的实用性。
