Abstract：
UNASSIGNED: This study aimed to systematically analyze the existing literature and conduct a meta-analysis on the acute effects of apnea on the hematological response by assessing changes in hemoglobin (Hb) concentration and hematocrit (Hct) values.
UNASSIGNED: Searches in Pubmed, The Cochrane Library, and Web of Science were carried out for studies in which the main intervention was voluntary hypoventilation, and Hb and Hct values were measured. Risk of bias and quality assessments were performed.
UNASSIGNED: Nine studies with data from 160 participants were included, involving both subjects experienced in breath-hold sports and physically active subjects unrelated to breath-holding activities. The GRADE scale showed a \"high\" confidence for Hb concentration, with a mean absolute effect of 0.57 g/dL over control interventions. \"Moderate\" confidence appeared for Hct, where the mean absolute effect was 2.45% higher over control interventions. Hb concentration increased to a greater extent in the apnea group compared to the control group (MD = 0.57 g/dL [95% CI 0.28, 0.86], Z = 3.81, p = 0.0001) as occurred with Hct (MD = 2.45% [95% CI 0.98, 3.93], Z = 3.26, p = 0.001).
UNASSIGNED: Apnea bouts lead to a significant increase in the concentration of Hb and Hct with a high and moderate quality of evidence, respectively. Further trials on apnea and its application to different settings are needed.
UNASSIGNED: Searches in Pubmed, The Cochrane Library, and Web of Science were carried out for studies in which the main intervention was voluntary hypoventilation, and Hb and Hct values were measured. Risk of bias and quality assessments were performed.
UNASSIGNED: Nine studies with data from 160 participants were included, involving both subjects experienced in breath-hold sports and physically active subjects unrelated to breath-holding activities. The GRADE scale showed a \"high\" confidence for Hb concentration, with a mean absolute effect of 0.57 g/dL over control interventions. \"Moderate\" confidence appeared for Hct, where the mean absolute effect was 2.45% higher over control interventions. Hb concentration increased to a greater extent in the apnea group compared to the control group (MD = 0.57 g/dL [95% CI 0.28, 0.86], Z = 3.81, p = 0.0001) as occurred with Hct (MD = 2.45% [95% CI 0.98, 3.93], Z = 3.26, p = 0.001).
UNASSIGNED: Apnea bouts lead to a significant increase in the concentration of Hb and Hct with a high and moderate quality of evidence, respectively. Further trials on apnea and its application to different settings are needed.
摘要：
■本研究旨在系统分析现有文献，并通过评估血红蛋白（Hb）浓度和血细胞比容（Hct）值的变化，对呼吸暂停对血液学反应的急性影响进行荟萃分析。
■在Pubmed中搜索，科克伦图书馆,和WebofScience进行了主要干预措施是自愿通气不足的研究，测量Hb和Hct值。进行偏倚风险和质量评估。
■纳入了来自160名参与者的9项研究，涉及在屏气运动中经历过的受试者和与屏气活动无关的身体活动受试者。量表显示Hb浓度的“高”置信度，与对照干预措施相比，平均绝对效应为0.57g/dL。“适度”的信心出现了Hct，其中平均绝对效应比对照干预高2.45%。与对照组相比，呼吸暂停组的Hb浓度增加幅度更大（MD=0.57g/dL[95％CI0.28，0.86]，Z=3.81，p=0.0001），如Hct（MD=2.45%[95%CI0.98，3.93]，Z=3.26，p=0.001）。
■呼吸暂停导致Hb和Hct浓度显着增加，证据质量高和中等，分别。需要对呼吸暂停及其在不同设置中的应用进行进一步的试验。
■在Pubmed中搜索，科克伦图书馆,和WebofScience进行了主要干预措施是自愿通气不足的研究，测量Hb和Hct值。进行偏倚风险和质量评估。
■纳入了来自160名参与者的9项研究，涉及在屏气运动中经历过的受试者和与屏气活动无关的身体活动受试者。量表显示Hb浓度的“高”置信度，与对照干预措施相比，平均绝对效应为0.57g/dL。“适度”的信心出现了Hct，其中平均绝对效应比对照干预高2.45%。与对照组相比，呼吸暂停组的Hb浓度增加幅度更大（MD=0.57g/dL[95％CI0.28，0.86]，Z=3.81，p=0.0001），如Hct（MD=2.45%[95%CI0.98，3.93]，Z=3.26，p=0.001）。
■呼吸暂停导致Hb和Hct浓度显着增加，证据质量高和中等，分别。需要对呼吸暂停及其在不同设置中的应用进行进一步的试验。
