Abstract：
BACKGROUND: In recent years, in-depth research has revealed that gut microbiota has an inseparable relationship with erectile dysfunction (ED) in men.
OBJECTIVE: (1) To review the correlation between gut microbiota and ED from the perspective of its impact on men\'s mental health, metabolism, immunity, and endocrine regulation and (2) to provide reference to further explore the pathogenesis of ED and the improvement of clinical treatment plans.
METHODS: PubMed was used for the literature search to identify publications related to ED and gut microbiota.
RESULTS: Gut microbiota may induce depression and anxiety through the microbiota-gut-brain axis, leading to the occurrence of psychological ED. It may also cause vascular endothelial dysfunction and androgen metabolism disorder by interfering with lipid metabolism, immunity, and endocrine regulation, leading to the occurrence of organic ED.
CONCLUSIONS: Gut microbiota and its metabolites play an important role in the occurrence and development of ED. As a new influencing factor of ED, gut microbiota disorder is expected to become a target for treatment.
OBJECTIVE: (1) To review the correlation between gut microbiota and ED from the perspective of its impact on men\'s mental health, metabolism, immunity, and endocrine regulation and (2) to provide reference to further explore the pathogenesis of ED and the improvement of clinical treatment plans.
METHODS: PubMed was used for the literature search to identify publications related to ED and gut microbiota.
RESULTS: Gut microbiota may induce depression and anxiety through the microbiota-gut-brain axis, leading to the occurrence of psychological ED. It may also cause vascular endothelial dysfunction and androgen metabolism disorder by interfering with lipid metabolism, immunity, and endocrine regulation, leading to the occurrence of organic ED.
CONCLUSIONS: Gut microbiota and its metabolites play an important role in the occurrence and development of ED. As a new influencing factor of ED, gut microbiota disorder is expected to become a target for treatment.
摘要：
背景：近年来，深入研究表明，肠道菌群与男性勃起功能障碍（ED）有着不可分割的关系。
目的：(1)从肠道菌群对男性心理健康的影响角度综述肠道菌群与ED的相关性,新陈代谢，豁免权,(2)为进一步探讨ED的发病机制及临床治疗方案的改进提供参考。
方法：使用PubMed进行文献检索，以确定与ED和肠道微生物群相关的出版物。
结果：肠道菌群可能通过菌群-肠-脑轴诱导抑郁和焦虑，导致心理性ED的发生。它还可能通过干扰脂质代谢而引起血管内皮功能障碍和雄激素代谢紊乱，豁免权,和内分泌调节，导致有机ED的发生。
结论：肠道菌群及其代谢产物在ED的发生和发展中起重要作用。作为ED的一个新的影响因素,肠道菌群紊乱有望成为治疗的目标。
目的：(1)从肠道菌群对男性心理健康的影响角度综述肠道菌群与ED的相关性,新陈代谢，豁免权,(2)为进一步探讨ED的发病机制及临床治疗方案的改进提供参考。
方法：使用PubMed进行文献检索，以确定与ED和肠道微生物群相关的出版物。
结果：肠道菌群可能通过菌群-肠-脑轴诱导抑郁和焦虑，导致心理性ED的发生。它还可能通过干扰脂质代谢而引起血管内皮功能障碍和雄激素代谢紊乱，豁免权,和内分泌调节，导致有机ED的发生。
结论：肠道菌群及其代谢产物在ED的发生和发展中起重要作用。作为ED的一个新的影响因素,肠道菌群紊乱有望成为治疗的目标。
