OBJECTIVE: To determine the relationship between pre-anesthetic anxiety and EA after radical surgery in patients with non-small cell lung cancer (NSCLC).
METHODS: Eighty patients with NSCLC undergoing surgical treatment between June 2020 and June 2023 were conveniently sampled. We used the Hospital Anxiety and Depression Scale\'s (HADS) anxiety subscale (HADS-A) to determine patients\' anxiety at four time points (T1-T4): Patients\' preoperative visit, waiting period in the surgical waiting room, after entering the operating room, and before anesthesia induction, respectively. The Riker Sedation-Agitation Scale (RSAS) examined EA after surgery. Scatter plots of HADS-A and RSAS scores assessed the correlation between patients\' pre-anesthesia anxiety status and EA. We performed a partial correlation analysis of HADS-A scores with RSAS scores.
RESULTS: NSCLC patients\' HADS-A scores gradually increased at the four time points: 7.33 ± 2.03 at T1, 7.99 ± 2.22 at T2, 8.05 ± 2.81 at T3, and 8.36 ± 4.17 at T4. The patients\' postoperative RSAS score was 4.49 ± 1.18, and 27 patients scored ≥ 5, indicating that 33.75% patients had EA. HADS-A scores at T3 and T4 were significantly higher in patients with EA (9.67 ± 3.02 vs 7.23 ± 2.31, 12.56 ± 4.10 vs 6.23 ± 2.05, P < 0.001). Scatter plots showed the highest correlation between HADS-A and RSAS scores at T3 and T4. Partial correlation analysis showed a strong positive correlation between HADS-A and RSAS scores at T3 and T4 (r = 0.296, 0.314, P < 0.01).
CONCLUSIONS: Agitation during anesthesia recovery in patients undergoing radical resection for NSCLC correlated with anxiety at the time of entering the operating room and before anesthesia induction.
目的:探讨非小细胞肺癌(NSCLC)患者术后麻醉前焦虑与EA的关系。
方法:对2020年6月至2023年6月期间80例接受手术治疗的非小细胞肺癌患者进行方便采样。我们使用医院焦虑和抑郁量表(HADS)焦虑子量表(HADS-A)来确定患者在四个时间点(T1-T4)的焦虑:患者术前访视,在手术候诊室的等待期,进入手术室后,在麻醉诱导前,分别。Riker镇静激动量表(RSAS)检查了手术后的EA。HADS-A和RSAS评分的散点图评估了患者麻醉前焦虑状态与EA之间的相关性。我们对HADS-A评分与RSAS评分进行了偏相关分析。
结果:NSCLC患者\'HADS-A评分在4个时间点逐渐升高:T1时7.33±2.03,T2时7.99±2.22,T3时8.05±2.81,T4时8.36±4.17。患者术后RSAS评分为4.49±1.18,有27例患者评分≥5,表明33.75%的患者患有EA。EA患者T3和T4时的HADS-A评分明显高于EA患者(9.67±3.02比7.23±2.31,12.56±4.10比6.23±2.05,P<0.001)。散点图显示T3和T4时HADS-A和RSAS评分之间的相关性最高。偏相关分析显示,T3和T4时HADS-A与RSAS评分呈较强的正相关(r=0.296、0.314,P<0.01)。
结论:非小细胞肺癌根治术患者在麻醉恢复期间的躁动与进入手术室时和麻醉诱导前的焦虑相关。