PDF(Pubmed)
Abstract：
UNASSIGNED: Zoledronate is a commonly prescribed medication to maintain bone health; however, a rare side effect includes ocular inflammation. We report a case of simultaneous anterior uveitis and orbital inflammation associated with zoledronate infusion in a patient with metastatic breast cancer. We also performed a literature search to provide an up-to-date summary of cases with zoledronate-associated ocular inflammation.
UNASSIGNED: This is a case report with literature review. Literature search (timeline 2010 to 2023) was performed using PubMed with the search team: (zoledronate) AND (uveitis OR scleritis OR orbital inflammation OR ocular inflammation).
UNASSIGNED: A 48-year-old female presented with left eye pain, swelling, and decreased vision 2 days after receiving zoledronic acid infusion. An ophthalmic exam showed non-granulomatous anterior uveitis. CT orbits and ocular ultrasound showed signs of posterior scleritis and orbital inflammation. Ocular inflammation caused by an infection or metastatic cancer was ruled out. The patient was treated with both topical and systemic corticosteroids. Complete resolution of the inflammation occurred after 2.5 weeks.
UNASSIGNED: Orbital inflammation and uveitis are an uncommon side effect of zoledronate but needs to be promptly recognized and treated to prevent sight-threatening complications.
UNASSIGNED: This is a case report with literature review. Literature search (timeline 2010 to 2023) was performed using PubMed with the search team: (zoledronate) AND (uveitis OR scleritis OR orbital inflammation OR ocular inflammation).
UNASSIGNED: A 48-year-old female presented with left eye pain, swelling, and decreased vision 2 days after receiving zoledronic acid infusion. An ophthalmic exam showed non-granulomatous anterior uveitis. CT orbits and ocular ultrasound showed signs of posterior scleritis and orbital inflammation. Ocular inflammation caused by an infection or metastatic cancer was ruled out. The patient was treated with both topical and systemic corticosteroids. Complete resolution of the inflammation occurred after 2.5 weeks.
UNASSIGNED: Orbital inflammation and uveitis are an uncommon side effect of zoledronate but needs to be promptly recognized and treated to prevent sight-threatening complications.
摘要：
■唑来膦酸盐是维持骨骼健康的常用处方药；然而，一种罕见的副作用包括眼部炎症。我们报告了一例转移性乳腺癌患者与唑来膦酸盐输注相关的同时发生的前葡萄膜炎和眼眶炎症。我们还进行了文献检索，以提供唑来膦酸盐相关眼部炎症病例的最新摘要。
■这是一例病例报告，并进行文献复习。使用PubMed与搜索团队进行文献搜索（时间表2010至2023年）：（唑来膦酸）和（葡萄膜炎或巩膜炎或眼眶炎症或眼部炎症）。
■一名48岁女性出现左眼疼痛,肿胀,接受唑来膦酸输注后2天视力下降。眼科检查显示非肉芽肿性前葡萄膜炎。CT眼眶和眼部超声显示后巩膜炎和眼眶炎症的征象。排除了由感染或转移性癌症引起的眼部炎症。患者接受局部和全身皮质类固醇治疗。炎症在2.5周后完全缓解。
■眼眶炎症和葡萄膜炎是唑来膦酸的罕见副作用，但需要及时识别和治疗以防止危及视力的并发症。
■这是一例病例报告，并进行文献复习。使用PubMed与搜索团队进行文献搜索（时间表2010至2023年）：（唑来膦酸）和（葡萄膜炎或巩膜炎或眼眶炎症或眼部炎症）。
■一名48岁女性出现左眼疼痛,肿胀,接受唑来膦酸输注后2天视力下降。眼科检查显示非肉芽肿性前葡萄膜炎。CT眼眶和眼部超声显示后巩膜炎和眼眶炎症的征象。排除了由感染或转移性癌症引起的眼部炎症。患者接受局部和全身皮质类固醇治疗。炎症在2.5周后完全缓解。
■眼眶炎症和葡萄膜炎是唑来膦酸的罕见副作用，但需要及时识别和治疗以防止危及视力的并发症。
