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Abstract：
Coronary artery ectasia (CAE) is a rare condition, affecting 3%-8% of patients with atherosclerotic coronary artery disease, and is characterized by the abnormal dilatation of the coronary arteries. While the etiology of coronary artery ectasia encompasses a myriad of acquired and genetic factors, its pathogenesis still remains a subject of investigation. The clinical manifestations are varied, ranging from asymptomatic cases to chest angina and myocardial infarction. Coronary angiography remains the gold standard for diagnosing CAE. We herein report four cases of coronary ectasia: the first involving myocardial infarction, the second associated with bicuspid aortic valve with severe aortic regurgitation, the third detected during coronary angiography for moderate left ventricular dysfunction, and the last one detected during coronary angiography for stable angina. The aims of our study are to highlight the diversity of clinical presentations as well as the challenge of management, given that there are no universal treatments or guidelines.
摘要：
冠状动脉扩张症（CAE）是一种罕见的疾病，影响3%-8%的动脉粥样硬化性冠状动脉疾病患者，以冠状动脉异常扩张为特征。虽然冠状动脉扩张症的病因包括无数的获得性和遗传因素，其发病机制仍是研究的课题。临床表现多种多样，从无症状病例到胸部心绞痛和心肌梗死。冠状动脉造影仍是诊断CAE的金标准。我们在此报告四例冠状动脉扩张：首例涉及心肌梗死，第二个与二叶主动脉瓣伴严重主动脉瓣反流有关，第三个在冠状动脉造影期间检测到中度左心功能不全，以及在冠状动脉造影期间发现的最后一个稳定型心绞痛。我们研究的目的是强调临床表现的多样性以及管理的挑战，鉴于没有普遍的治疗或指南。
