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Abstract：
In the last decade, several studies have explored various modalities and strategies for colorectal cancer (CRC) screening, taking into account epidemiological data, individual characteristics, and socioeconomic factors. In this editorial, we comment further on a retrospective study by Agatsuma et al published in the recent issue of the World Journal of Gastroenterology. Our focus is on screening trends, particularly in relation to efforts to improve the currently suboptimal uptake among the general population worldwide, aiming to enhance early diagnosis rates of CRC. There is a need to raise awareness through health edu-cation programs and to consider the use of readily available, non-invasive screening methods. These strategies are crucial for attracting screen-eligible populations to participate in first-line screening, especially those in high- or average-risk groups and in regions with limited resources. Liquid biopsies and biomarkers represent rapidly evolving trends in screening and diagnosis; however, their clinical relevance has yet to be standardized.
摘要：
在过去的十年里，几项研究探索了结直肠癌（CRC）筛查的各种方式和策略，考虑到流行病学数据，个体特征,和社会经济因素。在这篇社论中，我们进一步评论Agatsuma等人发表在最近一期的《世界胃肠病学杂志》上的一项回顾性研究。我们的重点是筛选趋势，特别是在努力改善全球普通人群目前的次优摄取方面，旨在提高CRC的早期诊断率。有必要通过健康教育计划提高认识，并考虑使用现成的，非侵入性筛查方法。这些策略对于吸引符合筛查资格的人群参与一线筛查至关重要，特别是那些高风险或中等风险群体以及资源有限的地区。液体活检和生物标志物代表了筛查和诊断的快速发展趋势；然而，其临床相关性尚未标准化.
