METHODS: A 25-year-old female exhibited symptoms of diabetes insipidus. Magnetic resonance imaging revealed an enhanced foci in the pituitary gland. After surgical resection of the pituitary lesion, the pathological diagnosis was chronic inflammation. However, the patient later experienced bone destruction in the skull and lower limb bones. After the lower limb bone lesion was compared with the initial pituitary lesion, the final diagnosis was modified to LCH. The patient was treated with multiple chemotherapy courses. However, the patient\'s condition gradually worsened, and she eventually passed away at home.
CONCLUSIONS: LCH should be considered when patients exhibit diabetes insipidus and absence of high signal intensity in the pituitary gland on sagittal T1-weighted image and abnormal enhancement in the pituitary region.
方法:一名25岁女性出现尿崩症症状。磁共振成像显示垂体中的病灶增强。手术切除垂体病变后,病理诊断为慢性炎症。然而,患者后来经历了颅骨和下肢骨的破坏。将下肢骨病变与最初的垂体病变进行比较后,最终诊断改为LCH.患者接受了多个化疗疗程。然而,病人的病情逐渐恶化,她最终还是在家里去世了.
结论:当患者表现为尿崩症,在矢状T1加权图像上垂体腺中没有高信号强度和垂体区域异常增强时,应考虑LCH。