PDF(Pubmed)
Abstract：
We report a case of a 69-year-old woman with pleural mesothelioma presenting in the posterior mediastinum with a maximum diameter of 25 cm. She had a chronic cough and a pleural effusion was noted on chest X-ray. The examination of the effusion showed high hyaluronic acid levels, and mesothelioma was suspected. A chest computed tomography scan showed a huge mediastinal mass, which caused rapid progression of respiratory failure and compression of the heart. Sufficient tissue samples could not be obtained before death. The patient died approximately 1 month after the initial visit, and a pathological autopsy was performed. The diagnosis of malignant pleural mesothelioma was made. Malignant pleural mesothelioma with a huge posterior mediastinal mass such as in this case is considerably rare; however, it is a rapidly progressing form of the disease and is reported here as an important differential diagnosis for mediastinal tumours.
摘要：
我们报告了一例69岁的女性，其胸膜间皮瘤出现在后纵隔，最大直径为25厘米。她患有慢性咳嗽，胸部X光检查发现胸腔积液。对积液的检查显示高透明质酸水平，和间皮瘤被怀疑。胸部计算机断层扫描显示纵隔巨大肿块，导致呼吸衰竭和心脏受压的快速进展。死亡前无法获得足够的组织样本。患者在初次就诊后约1个月死亡，并进行了病理尸检。诊断为恶性胸膜间皮瘤。恶性胸膜间皮瘤与巨大的后纵隔肿块，如在这种情况下是相当罕见的;然而，它是该疾病的一种快速发展形式，在本文中被报道为纵隔肿瘤的重要鉴别诊断。
