关键词: BRAF inhibitor MEK inhibitor bevacizumab chemotherapy immunotherapy low grade glioma optic pathway glioma stereotactic radiation

来  源:   DOI:10.3389/fopht.2022.992673   PDF(Pubmed)

Abstract:
Optic pathway gliomas (OPG) are primary tumors of the optic nerve, chiasm, and/or tract that can be associated with neurofibromatosis type 1 (NF1). OPG generally have a benign histopathology, but a variable clinical course. Observation is generally recommended at initial diagnosis if vision is stable or normal for age, however, treatment may include chemotherapy, radiotherapy, or surgery in select cases. This manuscript reviews the literature on OPG with an emphasis on recent developments in treatment.
摘要:
视路胶质瘤(OPG)是视神经的原发性肿瘤,chiasm,和/或可与1型神经纤维瘤病(NF1)相关的管道。OPG通常具有良性组织病理学,而是一个可变的临床过程。如果视力稳定或年龄正常,通常建议在初始诊断时进行观察。然而,治疗可能包括化疗,放射治疗,或手术在选择的情况下。本手稿回顾了有关OPG的文献,重点介绍了治疗的最新进展。
公众号