PDF(Pubmed)
Abstract：
UNASSIGNED: This study aimed to assess visual acuity (VA) in Congenital Zika Syndrome (CZS)-children to evaluate visual loss. To that end we evaluated 41 CZS - children, from Rio de Janeiro using Teller Acuity Cards.
UNASSIGNED: To asses VA, we evaluated 41 CZS - children, from Rio de Janeiro using Teller Acuity Cards. The children had Zika virus-infection confirmed by reverse transcription-polymerase chain reaction (RT-PCR) or clinical evaluation.
UNASSIGNED: In 39 out of 41 (95%) children, the VA scores were below normative values, while in 10 cases, VA was only marginally below normal; in the remaining 29 cases, VA was more than 0.15 logMAR below the lower limit. There was no correlation between VA and the cognitive domain tasks, although there was a correlation between VA and motor domain tasks. Thirty-seven children performed at least one task in the cognitive set, while fourteen children did not perform any task in the motor set. Children with VA above the lower limit performed better in the cognitive and motor tasks.
UNASSIGNED: We concluded that ZIKV- infected children with CZS were highly VA impaired which correlated with motor performance, but not with cognitive performance. Part of the children had VA within the normal limits and displayed better performance in the cognitive and motor sets. Therefore, even if heavily impaired, most children had some degree of VA and visual function.
UNASSIGNED: To asses VA, we evaluated 41 CZS - children, from Rio de Janeiro using Teller Acuity Cards. The children had Zika virus-infection confirmed by reverse transcription-polymerase chain reaction (RT-PCR) or clinical evaluation.
UNASSIGNED: In 39 out of 41 (95%) children, the VA scores were below normative values, while in 10 cases, VA was only marginally below normal; in the remaining 29 cases, VA was more than 0.15 logMAR below the lower limit. There was no correlation between VA and the cognitive domain tasks, although there was a correlation between VA and motor domain tasks. Thirty-seven children performed at least one task in the cognitive set, while fourteen children did not perform any task in the motor set. Children with VA above the lower limit performed better in the cognitive and motor tasks.
UNASSIGNED: We concluded that ZIKV- infected children with CZS were highly VA impaired which correlated with motor performance, but not with cognitive performance. Part of the children had VA within the normal limits and displayed better performance in the cognitive and motor sets. Therefore, even if heavily impaired, most children had some degree of VA and visual function.
摘要：
■本研究旨在评估先天性寨卡综合症（CZS）儿童的视力（VA），以评估视力丧失。为此，我们评估了41名CZS儿童，从里约热内卢使用TellerAcuity卡。
■评估VA，我们评估了41名CZS儿童，从里约热内卢使用TellerAcuity卡。通过逆转录-聚合酶链反应（RT-PCR）或临床评估证实了儿童的寨卡病毒感染。
■在41个（95％）儿童中的39个中，VA得分低于标准值，而在10个案例中，VA仅略低于正常值；在其余29例中，VA比下限低0.15logMAR以上。VA和认知领域任务之间没有相关性，尽管VA和运动域任务之间存在相关性。37名儿童在认知集中执行了至少一项任务，而十四个孩子没有在马达装置中执行任何任务。VA高于下限的儿童在认知和运动任务中表现更好。
■我们得出的结论是，感染ZIKV的CZS儿童是高度VA受损的，这与运动表现相关，但不是认知表现。部分儿童的VA在正常范围内，并且在认知和运动方面表现出更好的表现。因此,即使严重受损，大多数儿童有一定程度的VA和视觉功能。
■评估VA，我们评估了41名CZS儿童，从里约热内卢使用TellerAcuity卡。通过逆转录-聚合酶链反应（RT-PCR）或临床评估证实了儿童的寨卡病毒感染。
■在41个（95％）儿童中的39个中，VA得分低于标准值，而在10个案例中，VA仅略低于正常值；在其余29例中，VA比下限低0.15logMAR以上。VA和认知领域任务之间没有相关性，尽管VA和运动域任务之间存在相关性。37名儿童在认知集中执行了至少一项任务，而十四个孩子没有在马达装置中执行任何任务。VA高于下限的儿童在认知和运动任务中表现更好。
■我们得出的结论是，感染ZIKV的CZS儿童是高度VA受损的，这与运动表现相关，但不是认知表现。部分儿童的VA在正常范围内，并且在认知和运动方面表现出更好的表现。因此,即使严重受损，大多数儿童有一定程度的VA和视觉功能。
