PDF(Pubmed)
Abstract：
BACKGROUND: Leiomyomas (LMs) are mesenchymal tumors that arise from smooth muscle cells. LMs most commonly arise in organs with an abundance of smooth muscle such as the uterus and gastrointestinal tract. Conversely, LMs are rarely detected in the head and neck region. In this study, we report a rare case of laryngeal LM (LLM) and summarized the clinical characteristics of reported LLMs to help clinicians better understand this rare disease and improve its diagnosis, treatment, and postoperative course.
METHODS: A 49-year-old man was admitted to our ENT outpatient clinic with a chief complaint of pharynx discomfort for 2 months. Laryngoscopy performed under topical anesthesia revealed a solitary, pink mass at the tubercle of epiglottis. Surgery via laryngeal endoscopy was performed under general anesthesia, and the lesion was excised easily. Positive immunohistochemical staining for desmin and smooth-muscle actin indicated a smooth muscle origin and the diagnosis was laryngeal leiomyoma. After surgery, the patient\'s condition was stable, and he was discharged 2 d after surgery. During the 1-year postoperative period, the patient\'s condition remained stable without evidence of recurrence.
CONCLUSIONS: Surgical resection is the preferred treatment for LLMs, its early diagnosis and differential diagnosis have important clinical significance.
METHODS: A 49-year-old man was admitted to our ENT outpatient clinic with a chief complaint of pharynx discomfort for 2 months. Laryngoscopy performed under topical anesthesia revealed a solitary, pink mass at the tubercle of epiglottis. Surgery via laryngeal endoscopy was performed under general anesthesia, and the lesion was excised easily. Positive immunohistochemical staining for desmin and smooth-muscle actin indicated a smooth muscle origin and the diagnosis was laryngeal leiomyoma. After surgery, the patient\'s condition was stable, and he was discharged 2 d after surgery. During the 1-year postoperative period, the patient\'s condition remained stable without evidence of recurrence.
CONCLUSIONS: Surgical resection is the preferred treatment for LLMs, its early diagnosis and differential diagnosis have important clinical significance.
摘要：
背景：平滑肌瘤（LM）是由平滑肌细胞引起的间充质肿瘤。LMs最常见于具有大量平滑肌的器官，例如子宫和胃肠道。相反，在头部和颈部区域中很少检测到LM。在这项研究中,我们报告了一个罕见的喉部LM（LLM）病例，并总结了报告的LLM的临床特征，以帮助临床医生更好地了解这种罕见疾病并提高其诊断，治疗,和术后过程。
方法：一名49岁的男子因主诉咽部不适进入我们的耳鼻喉科门诊2个月。在局部麻醉下进行的喉镜检查显示，会厌结节处的粉红色肿块。在全身麻醉下通过喉内镜进行手术，病灶很容易切除.结蛋白和平滑肌肌动蛋白的免疫组织化学染色阳性提示平滑肌起源，诊断为喉平滑肌瘤。手术后,病人病情稳定,术后2d出院。在术后1年期间，患者病情保持稳定，无复发迹象。
结论：手术切除是LLM的首选治疗方法，其早期诊断和鉴别诊断具有重要的临床意义。
方法：一名49岁的男子因主诉咽部不适进入我们的耳鼻喉科门诊2个月。在局部麻醉下进行的喉镜检查显示，会厌结节处的粉红色肿块。在全身麻醉下通过喉内镜进行手术，病灶很容易切除.结蛋白和平滑肌肌动蛋白的免疫组织化学染色阳性提示平滑肌起源，诊断为喉平滑肌瘤。手术后,病人病情稳定,术后2d出院。在术后1年期间，患者病情保持稳定，无复发迹象。
结论：手术切除是LLM的首选治疗方法，其早期诊断和鉴别诊断具有重要的临床意义。
