关键词: Clinical research Oral health Patient reported treatment outcomes Patient-centered care Quality of life Surrogate endpoints

来  源:   DOI:10.12998/wjcc.v12.i18.3281   PDF(Pubmed)

Abstract:
Conventional dentistry or periodontal research often ignores the human component in favor of clinical outcomes and biological causes. Clinical research is driven by the statistical significance of outcome parameters rather than the satisfaction level of the patient. In this context, patient-centric periodontal research (PCPR) is an approach that considers the patient´s feedback concerning their functional status, experience, clinical outcomes, and accessibility to their treatments. It is argued that data self-reported by the patient might have low reliability owing to the confounding effect of their personal belief, cultural background, and social and economic factors. However, literature has shown that the incorporation of \"patient-centric outcome\" components considerably enhances the validity and applicability of research findings. Variations in the results of different studies might be due to the use of different and non-standardized assessment tools. To overcome this problem, this editorial enlists various reliable tools available in the literature. In conclusion, we advocate that the focus of researchers should shift from mere periodontal research to PCPR so that the results can be effectively applied in clinical settings and the therapeutic strategy can also change from mere periodontal therapy to patient-centric periodontal therapy.
摘要:
传统的牙科或牙周研究通常忽略人体成分,而有利于临床结果和生物学原因。临床研究是由结果参数的统计意义而不是患者的满意度驱动的。在这种情况下,以患者为中心的牙周研究(PCCPR)是一种考虑患者对其功能状态的反馈的方法,经验,临床结果,以及他们治疗的可及性。有人认为,由于患者个人信念的混淆作用,患者自我报告的数据可能具有较低的可靠性,文化背景,以及社会和经济因素。然而,文献表明,"以患者为中心的结局"成分的加入大大提高了研究结果的有效性和适用性.不同研究结果的差异可能是由于使用了不同的和非标准化的评估工具。为了克服这个问题,这篇社论列举了文献中可用的各种可靠工具。总之,我们主张研究者的研究重点应该从单纯的牙周研究转移到PCPR,这样研究结果可以有效地应用于临床,治疗策略也可以从单纯的牙周治疗转变为以患者为中心的牙周治疗.
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