OBJECTIVE: To study the population characteristics, clinical features, treatment, and prognosis of gallstones in children.
METHODS: The clinical data of 44 children with gallstones admitted to The First Affiliated Hospital of Naval Medical University from August 2009 to August 2021 were collected, the children were followed up by telephone to monitor their prognoses. The follow-up ended in August 2023. The shortest follow-up time was 2 years and 6 months, whereas the longest was 13 years and 11 months. The population characteristics, general clinical characteristics, and treatments were retrospectively analyzed. The children were divided according to whether they underwent surgical gallbladder removal into an operation group (n = 28) and a non-operation group (n = 16), The effects of surgical gallbladder resection on the growth and development of children were analyzed.
RESULTS: The male-female ratio in the population was 6:5 and 84.09% of the children had onset in adolescence. Furthermore, 29.55% of the children were overweight or obese. The study identified 26 cases with metabolic abnormalities, 9 with hemolytic anemia, and 4 with choledochal cyst. Of the population, 68.18% had recurrent symptomatic cholecystolithiasis. Surgical treatment accounted for 63.64%, with laparoscopic cholecystectomy accounting for 71.43% of surgical treatment. No significant differences were observed in symptoms and complications between the surgery and non-surgery groups. Furthermore, no significant differences were found between the two groups in the attainment of genetic height target and the rightward shift of height curve during follow-up.
CONCLUSIONS: The sex characteristics of gallstones in children were not observed. Most gallstones occurred in adolescents and rarely in young children. A considerable proportion of children have inborn causes, which are often concurrent with metabolic abnormalities and hemolytic anemia. Most children had recurrent symptomatic gallstones. Surgical treatment, especially laparoscopic cholecystectomy, is still the main treatment for gallstones in children. Surgical treatment did not affect the growth and development of children who underwent gallstone removal.
目的:为了研究人口特征,临床特征,治疗,和儿童胆结石的预后。
方法:收集2009年8月至2021年8月海军医科大学第一附属医院收治的44例胆结石患儿的临床资料。孩子们被电话跟踪,以监测他们的预后。后续行动于2023年8月结束。最短随访时间为2年6个月,而最长的是13年11个月。人口特征,一般临床特征,并对治疗方法进行回顾性分析。根据是否行胆囊切除手术分为手术组(n=28)和非手术组(n=16),分析手术胆囊切除术对患儿生长发育的影响。
结果:人口中的男女比例为6:5,84.09%的儿童在青春期发病。此外,29.55%的儿童超重或肥胖。该研究确定了26例代谢异常,9患有溶血性贫血,4例胆总管囊肿.在人口中,68.18%的患者有复发性症状胆囊结石。手术治疗占63.64%,腹腔镜胆囊切除术占手术治疗的71.43%。手术组与非手术组之间的症状和并发症没有显着差异。此外,在随访期间,两组在遗传身高目标的实现和身高曲线的右移方面没有发现显着差异。
结论:未观察到儿童胆结石的性别特征。大多数胆结石发生在青少年中,很少发生在幼儿中。相当比例的儿童有先天原因,常伴有代谢异常和溶血性贫血。大多数儿童有复发性症状的胆结石。手术治疗,尤其是腹腔镜胆囊切除术,仍然是儿童胆结石的主要治疗方法。手术治疗不影响胆结石切除患儿的生长发育。