UNASSIGNED: The study outcomes were 10-year all-cause mortality (sample number = 9,984) and 10-year heart diseases (sample number = 7,496). The exposure was the change of social activity frequency. Cox regression analysis was used for data analysis.
UNASSIGNED: During the follow-up, there were 6,407 all-cause mortalities and 1,035 heart diseases, respectively. Kaplan-Meier analysis demonstrated that cumulative incidences of all-cause mortality were significantly lower in participants with changes into more frequent social activity (log-rank p < 0.001), while no significant difference was observed for heart diseases (log-rank p = 0.330). Compared with the subgroup who never participated in social activity at baseline, adjusted HRs of all-cause mortality were 0.79 (95% CI: 0.70-0.90, p < 0.001), 0.78 (95% CI: 0.63-0.96, p = 0.019), 0.74 (0.59-0.92, p = 0.006), and 0.70 (95% CI: 0.56-0.88, p = 0.002) for the subgroup of switching to sometimes, the subgroup of switching to once a month, the subgroup of switching to once a week, and the subgroup of switching to everyday, respectively. The corresponding HRs of heart diseases were 0.83 (95% CI: 0.65-1.08, p = 0.170), 0.82 (95% CI: 0.51-1.31, p = 0.412), 0.91 (0.58-1.42, p = 0.675) and 0.75 (95% CI: 0.47-1.20, p = 0.227), respectively. Stratified and sensitivity analyses revealed similar results.
UNASSIGNED: Among older people who never participated in social activity, increased participation in social activity in later life was associated with reduced risk of all-cause mortality, but was not associated with reduced risk of heart diseases.
■研究结果是10年全因死亡率(样本数=9,984)和10年心脏病(样本数=7,496)。暴露是社会活动频率的变化。采用Cox回归分析进行数据分析。
■在随访期间,全因死亡率6407例,心脏病1035例,分别。Kaplan-Meier分析表明,随着社会活动的频繁变化,参与者的全因死亡率累积发生率显着降低(log-rankp<0.001)。而心脏疾病没有观察到显著差异(log-rankp=0.330)。与基线时从未参加过社交活动的亚组相比,全因死亡率的校正HR为0.79(95%CI:0.70-0.90,p<0.001),0.78(95%CI:0.63-0.96,p=0.019),0.74(0.59-0.92,p=0.006),和0.70(95%CI:0.56-0.88,p=0.002)的亚组切换到有时,每月切换一次的子组,每周切换一次的子组,以及切换到日常的子群,分别。心脏病的相应HR为0.83(95%CI:0.65-1.08,p=0.170),0.82(95%CI:0.51-1.31,p=0.412),0.91(0.58-1.42,p=0.675)和0.75(95%CI:0.47-1.20,p=0.227),分别。分层和敏感性分析显示出类似的结果。
■在从未参加过社交活动的老年人中,在以后的生活中参与社会活动的增加与全因死亡的风险降低有关,但与心脏病风险降低无关。