PDF(Pubmed)
Abstract：
UNASSIGNED: This retrospective cohort study presents a group of patients who underwent laser therapy for retinopathy of prematurity and presented with delayed anterior segment complications.
UNASSIGNED: The charts of infants treated with laser photocoagulation for retinopathy of prematurity at our institution between 1988 and 2020 were reviewed. The data extracted included demographics, treatment and clinical examination findings, and those on visual acuity, surgical procedures, and cycloplegic refraction. The inclusion criteria were documented anterior segment changes during the follow-up period. The exclusion criteria were any prior intraocular surgery or inflammation before signs of anterior segment complications developed. The exposure was laser photocoagulation for retinopathy of prematurity and the main outcomes were anterior segment complications, visual acuity, and cycloplegic refraction.
UNASSIGNED: A total of 183 charts were reviewed. Sixteen eyes of nine patients (4.4%) met the inclusion criteria. The mean follow-up period after laser treatment was 15.9 years (range 10 years-26 years). The mean gestational age at birth was 24.6 weeks (range 23 weeks-27 weeks), and the mean age at first clinical documentation of anterior segment complications was 8.7 years (range 1 years-25 years). The complications included cataract (n = five patients/eight eyes) and glaucoma (n = three patients/five eyes), with the most frequent complication being band keratopathy (n = nine patients/15 eyes). A total of five out of 16 eyes underwent surgical procedures due to anterior segment complications. After treatment, visual acuity improved back to its baseline value in four out of five of the treated eyes, and improved, but not to its baseline value, in one out of five of the treated eyes. All the patients developed progressive high myopia over the follow-up period.
UNASSIGNED: Anterior segment complications after laser photocoagulation for retinopathy of prematurity may develop later in life. They affect patients\' visual acuity and quality of life and may require treatment.
UNASSIGNED: The charts of infants treated with laser photocoagulation for retinopathy of prematurity at our institution between 1988 and 2020 were reviewed. The data extracted included demographics, treatment and clinical examination findings, and those on visual acuity, surgical procedures, and cycloplegic refraction. The inclusion criteria were documented anterior segment changes during the follow-up period. The exclusion criteria were any prior intraocular surgery or inflammation before signs of anterior segment complications developed. The exposure was laser photocoagulation for retinopathy of prematurity and the main outcomes were anterior segment complications, visual acuity, and cycloplegic refraction.
UNASSIGNED: A total of 183 charts were reviewed. Sixteen eyes of nine patients (4.4%) met the inclusion criteria. The mean follow-up period after laser treatment was 15.9 years (range 10 years-26 years). The mean gestational age at birth was 24.6 weeks (range 23 weeks-27 weeks), and the mean age at first clinical documentation of anterior segment complications was 8.7 years (range 1 years-25 years). The complications included cataract (n = five patients/eight eyes) and glaucoma (n = three patients/five eyes), with the most frequent complication being band keratopathy (n = nine patients/15 eyes). A total of five out of 16 eyes underwent surgical procedures due to anterior segment complications. After treatment, visual acuity improved back to its baseline value in four out of five of the treated eyes, and improved, but not to its baseline value, in one out of five of the treated eyes. All the patients developed progressive high myopia over the follow-up period.
UNASSIGNED: Anterior segment complications after laser photocoagulation for retinopathy of prematurity may develop later in life. They affect patients\' visual acuity and quality of life and may require treatment.
摘要：
这项回顾性队列研究介绍了一组因早产儿视网膜病变接受激光治疗并出现延迟性眼前节并发症的患者。
■回顾了1988年至2020年在我们机构接受激光光凝治疗早产儿视网膜病变的婴儿的图表。提取的数据包括人口统计，治疗和临床检查结果，和那些视力上的人，外科手术,和睫状肌麻痹屈光。纳入标准记录了随访期间的眼前节变化。排除标准是在眼前节并发症出现之前的任何先前眼内手术或炎症。早产儿视网膜病变的照射为激光光凝，主要结局为眼前节并发症，视敏度,和睫状肌麻痹屈光。
■共回顾了183张图表。9例患者的16只眼(4.4%)符合纳入标准。激光治疗后的平均随访期为15.9年（范围10年-26年）。出生时的平均胎龄为24.6周（范围为23周-27周），首次临床记录眼前节并发症的平均年龄为8.7岁(范围为1岁-25岁).并发症包括白内障(n=5例/8只眼)和青光眼(n=3例/5只眼),最常见的并发症是带状角膜病变（n=9例/15只眼）。由于眼前节并发症，总共16只眼睛中有5只接受了外科手术。治疗后,在五只接受治疗的眼睛中，有四只的视力恢复到其基线值，和改进,但没有达到它的基线值，五只被治疗的眼睛中就有一只。所有患者在随访期间均出现进行性高度近视。
■激光光凝术治疗早产儿视网膜病变后的前段并发症可能在以后的生活中发展。它们影响患者的视力和生活质量，可能需要治疗。
■回顾了1988年至2020年在我们机构接受激光光凝治疗早产儿视网膜病变的婴儿的图表。提取的数据包括人口统计，治疗和临床检查结果，和那些视力上的人，外科手术,和睫状肌麻痹屈光。纳入标准记录了随访期间的眼前节变化。排除标准是在眼前节并发症出现之前的任何先前眼内手术或炎症。早产儿视网膜病变的照射为激光光凝，主要结局为眼前节并发症，视敏度,和睫状肌麻痹屈光。
■共回顾了183张图表。9例患者的16只眼(4.4%)符合纳入标准。激光治疗后的平均随访期为15.9年（范围10年-26年）。出生时的平均胎龄为24.6周（范围为23周-27周），首次临床记录眼前节并发症的平均年龄为8.7岁(范围为1岁-25岁).并发症包括白内障(n=5例/8只眼)和青光眼(n=3例/5只眼),最常见的并发症是带状角膜病变（n=9例/15只眼）。由于眼前节并发症，总共16只眼睛中有5只接受了外科手术。治疗后,在五只接受治疗的眼睛中，有四只的视力恢复到其基线值，和改进,但没有达到它的基线值，五只被治疗的眼睛中就有一只。所有患者在随访期间均出现进行性高度近视。
■激光光凝术治疗早产儿视网膜病变后的前段并发症可能在以后的生活中发展。它们影响患者的视力和生活质量，可能需要治疗。
