PDF(Pubmed)
Abstract：
UNASSIGNED: To assess the effectiveness of topical allogeneic platelet-rich plasma (PRP) eye drops for the treatment of symptoms and clinical signs in patients with severe dry eye disease as a secondary condition caused by Sjögren\'s syndrome (SS).
UNASSIGNED: Case series and literature review.
UNASSIGNED: Six eyes from three consecutive patients with severe dry eye from SS were evaluated. The eyes were treated with allogeneic topical PRP eye drops, with one drop applied six times daily for 3 months. A post-treatment follow-up evaluation was conducted 3 months after treatment suspension. We evaluated subjective symptoms, visual acuity, tear breakup time, the results of Schirmer\'s I test, fluorescein corneal and conjunctival staining, and corneal sensitivity.
UNASSIGNED: The symptoms and visual acuity improved significantly in all patients. There was a significant improvement in corneal sensitivity and a decrease or disappearance of fluorescein corneal staining.
UNASSIGNED: The treatment with allogenic PRP eye drops of patients with SS-related severe dry eye disease has proven to be very effective, with an improvement in symptoms and main clinical signs.
UNASSIGNED: Case series and literature review.
UNASSIGNED: Six eyes from three consecutive patients with severe dry eye from SS were evaluated. The eyes were treated with allogeneic topical PRP eye drops, with one drop applied six times daily for 3 months. A post-treatment follow-up evaluation was conducted 3 months after treatment suspension. We evaluated subjective symptoms, visual acuity, tear breakup time, the results of Schirmer\'s I test, fluorescein corneal and conjunctival staining, and corneal sensitivity.
UNASSIGNED: The symptoms and visual acuity improved significantly in all patients. There was a significant improvement in corneal sensitivity and a decrease or disappearance of fluorescein corneal staining.
UNASSIGNED: The treatment with allogenic PRP eye drops of patients with SS-related severe dry eye disease has proven to be very effective, with an improvement in symptoms and main clinical signs.
摘要：
■评估局部使用同种异体富血小板血浆（PRP）滴眼液治疗严重干眼症患者的症状和临床体征的有效性。
■案例系列和文献综述。
■对3例SS严重干眼连续患者的6只眼进行了评估。用同种异体局部PRP滴眼液治疗眼睛，一滴，每天6次，持续3个月。治疗暂停后3个月进行治疗后随访评估。我们评估了主观症状，视敏度,眼泪破裂时间，Schirmer\我测试的结果,荧光素角膜和结膜染色，和角膜敏感性。
■所有患者的症状和视力均有明显改善。角膜敏感性显着改善，荧光素角膜染色减少或消失。
■使用同种异体PRP滴眼液治疗SS相关严重干眼症患者已被证明非常有效，症状和主要临床体征有所改善。
■案例系列和文献综述。
■对3例SS严重干眼连续患者的6只眼进行了评估。用同种异体局部PRP滴眼液治疗眼睛，一滴，每天6次，持续3个月。治疗暂停后3个月进行治疗后随访评估。我们评估了主观症状，视敏度,眼泪破裂时间，Schirmer\我测试的结果,荧光素角膜和结膜染色，和角膜敏感性。
■所有患者的症状和视力均有明显改善。角膜敏感性显着改善，荧光素角膜染色减少或消失。
■使用同种异体PRP滴眼液治疗SS相关严重干眼症患者已被证明非常有效，症状和主要临床体征有所改善。
