METHODS: A total of 200 patients with radical prostatectomy admitted to our hospital from January 2016 to January 2021 were retrospectively enrolled as observation objects. According to whether there was biochemical recurrence after surgery, the patients were divided into the abnormal group (n = 62) and normal group (n = 138). Clinical data, encapsulation infiltration, seminal vesicle infiltration and prostate imaging report and data system (PI-RADS) were collected and compared between the two groups. Propensity score matching (PSM) was used to balance the baseline data of the two groups. Student\'s t-test and Chi-square test were used to analyse the data.
RESULTS: PSM was performed in a 1:1 ratio, and a total of 72 patients were included in the abnormal and normal groups. The baseline data of the patients in each group were not statistically significant. The incidence of extraperitoneal invasion and seminal vesicle invasion was higher in the abnormal group than in the normal group, and we observed a significant difference in PI-RADS scores between the two groups (p < 0.05). Extracapsular invasion, seminal vesicle invasion, PI-RADS score and biochemical recurrence were significantly correlated (p < 0.05). The PI-RADS score has a high value for predicting biochemical recurrence, with an area under the curve value of 0.824, sensitivity of 0.667, specificity of 0.861 and Youden index of 0.528.
CONCLUSIONS: Bi-parametric magnetic resonance imaging has a high predictive value in biochemical recurrence after radical prostatectomy, which can provide reference for early intervention measures.
方法:回顾性选取我院2016年1月至2021年1月收治的200例前列腺癌根治术患者作为观察对象。根据手术后是否有生化复发,将患者分为异常组(n=62)和正常组(n=138)。临床数据,封装渗透,收集并比较两组患者的精囊浸润和前列腺影像学报告及数据系统(PI-RADS)。采用倾向评分匹配法(PSM)平衡两组基线资料。采用t检验和卡方检验对数据进行分析。
结果:PSM以1:1的比例进行,共有72例患者被纳入异常组和正常组。各组患者的基线数据无统计学意义。异常组腹膜外侵犯和精囊侵犯的发生率高于正常组,两组患者PI-RADS评分差异有统计学意义(p<0.05)。囊外侵入,精囊侵入,PI-RADS评分与生化复发显著相关(p<0.05)。PI-RADS评分对生化复发有较高的预测价值,曲线下面积值为0.824,敏感性为0.667,特异性为0.861,Youden指数为0.528。
结论:双参数磁共振成像对前列腺癌根治术后生化复发有很高的预测价值,为早期干预措施提供参考。