关键词: breast carcinoma cutaneous metastasis dermatopathology

来  源:   DOI:10.1111/cup.14688

Abstract:
Cutaneous metastasis is rare but may indicate an advanced internal malignancy or a recurrence of a previously treated one and is usually associated with a poor prognosis. They may also pose a diagnostic problem as the clinical manifestations are variable and non-specific, which could mimic other benign conditions. We report a case of a 48-year-old female who presented with a 4-year history of erythematous papules and vesicles on the trunk mimicking lymphangioma circumscriptum. Skin biopsy and immunohistochemistry were consistent with cutaneous metastasis from breast carcinoma. Cutaneous metastasis presents in a variety of patterns. A high index of suspicion and a low threshold for skin biopsy are paramount to the early diagnosis and treatment. A histopathologic evaluation will help identify the origin of the cutaneous metastasis and can significantly affect the outcome of the treatment.
摘要:
皮肤转移很少见,但可能表明晚期内部恶性肿瘤或先前治疗过的恶性肿瘤复发,通常与预后不良有关。由于临床表现是可变且非特异性的,因此它们也可能构成诊断问题。可以模仿其他良性条件。我们报告了一例48岁的女性,她的躯干上有4年的红斑丘疹和囊泡病史,模仿了淋巴管瘤。皮肤活检和免疫组织化学与乳腺癌皮肤转移一致。皮肤转移表现为多种模式。高度怀疑和皮肤活检的低阈值对于早期诊断和治疗至关重要。组织病理学评估将有助于确定皮肤转移的起源,并且可以显着影响治疗的结果。
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