Abstract：
Background: The normally acidic skin pH changes in atopic dermatitis (AD) to alkaline, which contributes to the associated skin-barrier dysfunction. Hence, acidic cleansers would be preferred, but such information is scarce. Objective: Guiding health-care providers and patients on selecting skin cleansers with a pH optimal for AD. Methods: A total of 250 products were tested: 37 soaps (32 bars, 5 liquid) and 213 syndets (14 bars, 199 liquid); 10% solutions were tested for pH by using a pH meter; pH values 6.65-7.35 were considered neutral. Results: The pH of the tested skin cleansers varied widely (3.59-10.83). All 37 soaps were highly alkaline. In the 14 syndet bars, the pH was neutral in 6, alkaline in 8, and acidic in none. In the 199 syndet liquids, the pH was acidic in 84.9%, neutral in 11.1%, and alkaline in 4.0%. The product\'s pH was disclosed in none of the 37 soaps and in only 32 syndets (15%) , of which 9 bars were labeled \"balanced,\" whose measured pH was neutral in 6 and alkaline in 3. Of the other 23 syndets, the labeled pH was referred to as \"balanced\" in 20 whose measured pH was neutral in 2 (6.80, 6.88) and acidic in 18 (3.59-6.59). The pH in the other three syndets was 4.25-6.00. Conclusion: All tested soaps had undesirable pH, whereas 84.9% of the liquid syndets were acidic (which is desirable) and 11.1% were neutral (which could be acceptable). Only 12.8% of the products disclosed the pH, an issue in need of improvement.
摘要：
背景：特应性皮炎（AD）的正常酸性皮肤pH值变化为碱性，这有助于相关的皮肤屏障功能障碍。因此，酸性清洁剂将是首选，但是这样的信息很少。目标：指导医疗保健提供者和患者选择pH值最佳的皮肤清洁剂。方法：总共测试了250种产品：37种肥皂（32条，5个液体)和213个同步件(14巴，199液体）；通过使用pH计测试10％溶液的pH；pH值6.65-7.35被认为是中性的。结果:测试的皮肤清洁剂的pH变化很大(3.59-10.83)。所有37种肥皂都是高度碱性的。在14个Syndet栏中，pH在6中为中性，在8中为碱性，在无酸性。在199个Syndet液体中，pH为酸性84.9%，中性11.1%，和碱性在4.0%。在37种肥皂中没有公开产品的pH值，只有32种（15%），其中9条被标记为“平衡”，“，其测得的pH在6中为中性，在3中为碱性。在其他23个辛迪加中，标记的pH在20中被称为“平衡”，其测量的pH在2中为中性（6.80，6.88），在18中为酸性（3.59-6.59）。其他三个合成酶的pH为4.25-6.00。结论：所有测试的肥皂都有不理想的pH值，而84.9%的液体合成物是酸性的(这是可取的)和11.1%是中性的(这是可以接受的)。只有12.8%的产品公开了pH值，一个需要改进的问题。
