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Abstract：
This study aimed to determine the mediation role of hope in the relationship of resilience with depression, anxiety, and stress in caregivers of children and adolescents with cancer. This cross-sectional study was conducted on 200 caregivers of children and adolescents with cancer. Adult Hope Scale, Connor-Davidson Resilience Scale, and Depression, Anxiety and Stress (DAS) scales were used for data collection. The mediator and moderator model was tested using the SPSS macro PROCESS (Model 4, and 5). The mediator model (model 4) indicated that DAS significantly correlated with resilience (β = - 0.54, t-value = - 5.01, p < 0.001), and hope (β = - 0.84, t-value = - 3.45, p = 0.0007). Hope mediated the relationship between resilience and DAS among caregivers of children and adolescents with cancer (Effect = - 0.18, SE = 0.06, 95% CI - 0.33 to - 0.06). The mediator and moderator model (model 5) showed that female caregivers had a stronger correlation between resilience and DAS when compared to their male counterparts (β = - 0.56, t-value = - 3.90, p-value = 0.0001); also, hope mediated the relationship between resilience and DAS among caregivers of children and adolescents with cancer (Effect = - 0.20, SE = 0.08, 95% CI - 0.37 to - 0.04). In conclusion, hope was a mediator, and female caregivers were a moderator in the relationship of resilience with depression, anxiety, and stress, and its promotion might be effective among caregivers of children and adolescents with cancer. It seems that resilience, female caregivers, and hope may provide good protection against depression, anxiety, and stress in caregivers of cancer patients.
摘要：
本研究旨在确定希望在韧性与抑郁关系中的中介作用。焦虑,以及癌症儿童和青少年照顾者的压力。这项横断面研究是对200名患有癌症的儿童和青少年的照顾者进行的。成人希望量表,康纳-戴维森弹性量表，和抑郁症,使用焦虑和压力（DAS）量表进行数据收集。使用SPSS宏过程（模型4和5）测试了中介和主持人模型。中介模型（模型4）表明DAS与弹性显着相关（β=-0.54，t值=-5.01，p<0.001），和希望(β=-0.84，t值=-3.45，p=0.0007)。希望介导了儿童和青少年癌症患者照顾者的韧性与DAS之间的关系（效应=-0.18，SE=0.06，95％CI-0.33至-0.06）。中介和调节模型（模型5）表明，与男性相比，女性照顾者在韧性和DAS之间具有更强的相关性（β=-0.56，t值=-3.90，p值=0.0001）；希望介导了患有癌症的儿童和青少年的照顾者之间的韧性和DAS之间的关系(效应=-0.20,SE=0.08,95%CI-0.37至-0.04)。总之,希望是调解人,女性护理人员是韧性与抑郁关系的调节者，焦虑,和压力，在患有癌症的儿童和青少年的照顾者中，其推广可能是有效的。似乎有韧性，女性看护人,希望可以为抑郁症提供良好的保护，焦虑,和癌症患者护理人员的压力。
