Abstract:
Allogeneic transplantation of haematopoietic stem cells is still the only curative treatment for certain haematological malignancies. This treatment can be responsible for a number of side-effects, leading to multiple and interdependent physical and psychological deficiencies that affect patients\' quality of life and social participation, and can be experienced as a handicap, sometimes for several years after the transplant. For several years now, the integration of post-transplant rehabilitation pathways has been becoming more widespread, and initiatives to provide multidisciplinary care at an increasingly early stage are being studied. The aim of this early management is to improve the patient\'s overall functional state before, during and after the transplant, in order to limit the impact of the treatment and ensure the quickest possible return to a life that is as satisfying as possible. The international literature and the experiments carried out throughout the French-speaking world describe heterogeneous practices. Based on this literature and experience, the aim of this study is to issue homogenous recommendations for good clinical practice and to identify areas for further research into pre-transplant, per-transplant and post-transplant rehabilitation of haematopoietic stem cells.
摘要:
造血干细胞的同种异体移植仍然是某些血液系统恶性肿瘤的唯一治愈性治疗方法。这种治疗可能导致许多副作用,导致多重和相互依存的身体和心理缺陷,影响患者的生活质量和社会参与,可以作为一个障碍来体验,有时移植后几年。几年来,移植后康复途径的整合变得越来越普遍,正在研究在越来越早的阶段提供多学科护理的举措。这种早期管理的目的是改善患者的整体功能状态,在移植期间和之后,以限制治疗的影响,并确保尽可能快地回到尽可能令人满意的生活。在整个法语世界中进行的国际文献和实验描述了异质实践。基于这些文献和经验,这项研究的目的是为良好的临床实践发布同质的建议,并确定进一步研究移植前的领域,造血干细胞的每次移植和移植后康复。