Abstract：
BACKGROUND: The objective of this experiment was to investigate the thermal effects on hyaluronic acid fillers, PCL fillers, and PDO threads when exposed to controlled heat. This study aims to provide insights into how these materials respond to thermal energy, which is crucial for safe and effective cosmetic procedures involving combined modalities.
METHODS: Cadaveric tissue was utilized to simulate clinical conditions. Hyaluronic acid fillers were injected at approximately 1 mm and 5 mm thicknesses, with variations in G\' value (high and low). PCL fillers were similarly injected in 1 mm and 5 mm thicknesses. PDO threads were also inserted. All materials were injected at a depth of 2 cm. A thermometer was used to measure heat penetration, and a multi-wavelength laser was applied to the tissue. The temperature was maintained at 60°C for 5 min to assess whether heat penetrated more than 3 cm in thickness. Observations were made regarding the heat distribution and any physical changes in the fillers and threads.
RESULTS: In thick layers, heat accumulated above the PCL filler without penetrating deeper layers. In thin layers, heat penetration was observed. For the HA fillers, heat energy was not blocked, regardless of the G\' value or thickness. For the threads, no significant heat blockage effect was observed. For all materials, no visual changes were detected in any of the materials due to temperature exposure.
CONCLUSIONS: The findings suggest that the thickness and composition of fillers significantly influence heat penetration. Thick PCL fillers act as a thermal barrier, whereas thin PCL fillers allow deeper heat penetration. Hyaluronic acid fillers do not impede heat transfer, regardless of their physical properties. PDO threads do not exhibit any notable thermal resistance. These insights are essential for optimizing the safety and efficacy of combined filler and energy-based device treatments in esthetic medicine.
METHODS: Cadaveric tissue was utilized to simulate clinical conditions. Hyaluronic acid fillers were injected at approximately 1 mm and 5 mm thicknesses, with variations in G\' value (high and low). PCL fillers were similarly injected in 1 mm and 5 mm thicknesses. PDO threads were also inserted. All materials were injected at a depth of 2 cm. A thermometer was used to measure heat penetration, and a multi-wavelength laser was applied to the tissue. The temperature was maintained at 60°C for 5 min to assess whether heat penetrated more than 3 cm in thickness. Observations were made regarding the heat distribution and any physical changes in the fillers and threads.
RESULTS: In thick layers, heat accumulated above the PCL filler without penetrating deeper layers. In thin layers, heat penetration was observed. For the HA fillers, heat energy was not blocked, regardless of the G\' value or thickness. For the threads, no significant heat blockage effect was observed. For all materials, no visual changes were detected in any of the materials due to temperature exposure.
CONCLUSIONS: The findings suggest that the thickness and composition of fillers significantly influence heat penetration. Thick PCL fillers act as a thermal barrier, whereas thin PCL fillers allow deeper heat penetration. Hyaluronic acid fillers do not impede heat transfer, regardless of their physical properties. PDO threads do not exhibit any notable thermal resistance. These insights are essential for optimizing the safety and efficacy of combined filler and energy-based device treatments in esthetic medicine.
摘要：
背景：本实验的目的是研究透明质酸填充剂的热效应，PCL填料,和PDO线暴露于受控热量时。这项研究旨在提供有关这些材料如何响应热能的见解，这对于涉及组合方式的安全有效的整容手术至关重要。
方法:利用尸体组织来模拟临床状况。注射厚度约为1毫米和5毫米的透明质酸填料，随着G值的变化(高和低)。以Imm和5mm的厚度类似地注入PCL填料。还插入了PDO线程。所有材料均以2cm的深度注射。用温度计测量热渗透，并对组织施加多波长激光。将温度在60°C下保持5分钟,以评估热穿透的厚度是否超过3cm。观察了填料和线的热分布和任何物理变化。
结果：在厚层中，在PCL填料上方积聚的热量没有穿透更深的层。在薄层中，观察到热渗透。对于HA填料，热能没有被阻断，无论G\'值或厚度。对于线程，没有观察到明显的热阻塞效应。对于所有材料，由于温度暴露,在任何材料中均未检测到视觉变化.
结论:研究结果表明填料的厚度和组成显著影响热渗透。厚的PCL填料充当热障，而薄的PCL填料允许更深的热渗透。透明质酸填料不妨碍传热，不管他们的物理特性。PDO螺纹不表现出任何显著的耐热性。这些见解对于优化美容医学中组合填充剂和基于能量的设备治疗的安全性和有效性至关重要。
方法:利用尸体组织来模拟临床状况。注射厚度约为1毫米和5毫米的透明质酸填料，随着G值的变化(高和低)。以Imm和5mm的厚度类似地注入PCL填料。还插入了PDO线程。所有材料均以2cm的深度注射。用温度计测量热渗透，并对组织施加多波长激光。将温度在60°C下保持5分钟,以评估热穿透的厚度是否超过3cm。观察了填料和线的热分布和任何物理变化。
结果：在厚层中，在PCL填料上方积聚的热量没有穿透更深的层。在薄层中，观察到热渗透。对于HA填料，热能没有被阻断，无论G\'值或厚度。对于线程，没有观察到明显的热阻塞效应。对于所有材料，由于温度暴露,在任何材料中均未检测到视觉变化.
结论:研究结果表明填料的厚度和组成显著影响热渗透。厚的PCL填料充当热障，而薄的PCL填料允许更深的热渗透。透明质酸填料不妨碍传热，不管他们的物理特性。PDO螺纹不表现出任何显著的耐热性。这些见解对于优化美容医学中组合填充剂和基于能量的设备治疗的安全性和有效性至关重要。
