PDF(Pubmed)
Abstract：
An 11-year-old female cinnamon cockatiel (Nymphicus hollandicus) was presented with a coelomic distention. Dystocia was suspected, given its previous history of a calcium-deficient diet and multiple instances of nonobstructive dystocia. Exploratory coeliotomy revealed a large intraluminal mass extending through the magnum to the uterus (shell gland). Metastasis and multiorgan involvement were not seen. Histopathologically, malignant and invasive fascicles of spindle cells were associated with abundant myxoid matrix and hypocellular areas. Multinucleation, bizarre cells and atypical mitotic figures were prominent. Masson\'s trichrome staining verified the muscular origin, and the myxoid matrix was demonstrated utilizing Alcian blue. The neoplastic cells exhibited alpha-smooth muscle actin and desmin immunoreactivity and were negative for vimentin. Thus, the patient was diagnosed with oviductal and uterine myxoid leiomyosarcoma (LMS). The patient survived 34 days post-surgery before death associated with suspected enteritis. Myxoid LMS is an extremely rare neoplasm in animals. To our knowledge, myxoid LMS has not been reported previously in pet birds.
摘要：
一名11岁的雌性肉桂鸟（Nymphicushollandicus）出现了体腔扩张。怀疑难产,鉴于其先前的缺钙饮食史和多次非梗阻性难产。探索性腹腔切开术显示有一个大的腔内肿块，该肿块延伸穿过子宫（壳腺）。未见转移和多器官受累。组织病理学,梭形细胞的恶性和侵袭性束与丰富的粘液样基质和低细胞区域有关。多核,奇异的细胞和不典型的有丝分裂图突出。Masson的三色染色证实了肌肉的起源，粘液样基质被证明是利用阿尔辛蓝。肿瘤细胞表现出α-平滑肌肌动蛋白和结蛋白免疫反应性，波形蛋白阴性。因此，患者被诊断为输卵管和子宫粘液样平滑肌肉瘤（LMS）。患者在手术后存活34天，然后死亡与疑似肠炎相关。粘液样LMS是动物中极为罕见的肿瘤。据我们所知,以前没有在宠物鸟中报道过粘液样LMS。
