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Abstract：
Extra-adrenal myelolipoma (EAM) is a rare benign tumor composed of mature adipose and hematopoietic tissues. Its etiology remains to be elucidated and there are few case reports describing the clinical features and treatment of EAMs in the central nervous system. The present study presented our experience and practice in the clinical management of a case of EAM in the right frontal region. A 56-year-old woman was found to have a space-occupying right frontal lesion on computed tomography (CT) of the head. Unenhanced magnetic resonance imaging (MRI) showed a lesion of ~1.5x1.2 cm. Enhanced whole abdominal CT showed a right presacral mass, 2.0 cm in diameter, with clear margins. The postoperative histopathological findings showed mainly mature adipose tissue mixed with extramedullary hematopoietic components. This confirmed the diagnosis of a (bone) marrow lipoma. Myelolipoma of the central nervous system is extremely rare. to the best of the authors\' knowledge, only two cases of intracranial myelolipoma have been reported, and the present study introduced the first case in a Chinese patient reported in English. However, when CT shows high density and MRI shows mixed density in the tumor area even without enhancement, the possibility of myelolipoma should be considered in the differential diagnosis.
摘要：
肾上腺外骨髓脂肪瘤（EAM）是一种罕见的良性肿瘤，由成熟的脂肪和造血组织组成。其病因仍有待阐明，很少有病例报道描述中枢神经系统EAM的临床特征和治疗。本研究介绍了我们在右额叶区域EAM病例的临床管理中的经验和实践。在头部计算机断层扫描（CT）上发现一名56岁的妇女患有占位性右额叶病变。未增强的磁共振成像（MRI）显示约1.5x1.2cm的病变。全腹增强CT显示右侧骶前肿块,直径2.0厘米，有明显的利润。术后组织病理学发现主要为成熟脂肪组织混合髓外造血成分。这证实了（骨）骨髓脂肪瘤的诊断。中枢神经系统髓质脂肪瘤极为罕见。据作者所知，只有两例颅内髓脂肪瘤被报道，本研究介绍了第一例以英语报道的中国患者。然而,当CT显示高密度和MRI显示混合密度在肿瘤区域，即使没有增强，在鉴别诊断中应考虑髓脂肪瘤的可能性。
