关键词: cartridge based nucleic acid amplification test (cbnaat) femur tb intramedullary abscesses mycobacterium tuberculosis (mtb) tuberculosis

来  源:   DOI:10.7759/cureus.61928   PDF(Pubmed)

Abstract:
Tuberculosis of the long bones/femur, especially in an immunocompetent person, is a challenging diagnosis. It is a rare entity, even in endemic settings. The non-specific clinical features, backed by a low suspicion about such presentations even in endemic settings, may result in delayed diagnosis and often unfavorable treatment outcomes. The situation becomes even more challenging in the absence of pulmonary foci and a contact history of tuberculosis. Here is a case of a young adult male who presented with complaints of pain over his left leg for three months. A diagnosis was achieved with magnetic resonance imaging and the isolation of the bacteria from a bone biopsy using a cartridge-based nucleic acid amplification test. Antituberculous treatment was promptly initiated.
摘要:
长骨/股骨结核,尤其是在一个有免疫能力的人身上,这是一个具有挑战性的诊断。这是一个罕见的实体,即使在地方性环境中。非特异性临床特征,即使在地方性环境中,对此类演示的怀疑也很低,可能导致延迟诊断和通常不利的治疗结果。在没有肺灶和结核病接触史的情况下,情况变得更具挑战性。这是一个年轻的成年男性的案例,他抱怨左腿疼痛三个月。通过磁共振成像和使用基于盒的核酸扩增测试从骨活检中分离细菌来实现诊断。及时开始抗结核治疗。
公众号