PDF(Pubmed)
Abstract：
Monkeypox is a zoonotic virus with an increasing incidence in Nigeria, posing significant public health challenges. The virus, related to smallpox, primarily spreads through direct contact with infected animals or humans and has been noted for its potential for wider transmission due to changing ecological and social dynamics. This research aims to evaluate the feasibility of eliminating monkeypox in Nigeria through integrated approaches involving vaccination, public health strategies, and ecological management. Additionally, it seeks to propose a unified public health strategy, incorporating One Health principles, to achieve the elimination of monkeypox in Nigeria. A review of the feasibility of eliminating the monkeypox virus in Nigeria was conducted using databases like Science Direct, Cochrane, PubMed, and Medline. The search was guided by the methodologies and reporting guidelines of the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA). The initial search yielded 89 publications, but the number of articles that required examination was reduced after applying selected keywords and evaluating abstracts. We deemed 32 articles relevant to the subject after applying inclusion and exclusion criteria. The findings are analyzed, highlighting their limitations and strengths and discussing practical implications, knowledge gaps, and recommendations for future research. This study provides evidence supporting the feasibility of the elimination of the monkeypox virus in Nigeria. Strategic recommendations for a sustainable public health approach to eliminating monkeypox emphasize preventive measures, community engagement, and ecological preservation. This study will provide critical insights into the feasibility of eliminating monkeypox in Nigeria, offering a model that can be adapted for other regions facing similar challenges. The integration of health, ecological, and community-focused strategies is expected to contribute significantly to global efforts to control and potentially eradicate monkeypox. This research could serve as a foundational study for public health authorities in Nigeria and internationally, informing policy and operational decisions to control and eliminate monkeypox as a public health threat. The monkeypox virus reemerges in Nigeria, increasing mortality rates. Awareness programs should be conducted on its danger, transmission mode, and potential human transmission. Public education on the lack of treatment and vaccines is crucial. Meat inspection laws should be enforced to ensure safe animal consumption.
摘要：
猴痘是一种人畜共患病毒，在尼日利亚发病率越来越高，构成重大公共卫生挑战。病毒,与天花有关,主要通过与受感染的动物或人类直接接触而传播，并且由于不断变化的生态和社会动态而具有更广泛的传播潜力。这项研究旨在评估通过涉及疫苗接种的综合方法在尼日利亚消除猴痘的可行性，公共卫生战略,和生态管理。此外,它寻求提出统一的公共卫生战略，纳入一个健康原则，在尼日利亚消除猴痘。使用ScienceDirect等数据库对消除尼日利亚猴痘病毒的可行性进行了审查，科克伦,PubMed,Medline搜索以系统评价和荟萃分析（PRISMA）的首选报告项目的方法和报告指南为指导。最初的搜索产生了89种出版物，但是在应用选定的关键词和评估摘要后，需要检查的文章数量减少了。在应用纳入和排除标准后，我们认为32篇文章与受试者相关。对调查结果进行了分析，突出它们的局限性和优势，讨论实际意义，知识差距，以及对未来研究的建议。这项研究提供了证据支持在尼日利亚消除猴痘病毒的可行性。消除猴痘的可持续公共卫生方法的战略建议强调预防措施，社区参与,和生态保护。这项研究将为消除尼日利亚猴痘的可行性提供重要见解，提供一种可以适应其他面临类似挑战的地区的模式。健康的整合，生态,以社区为中心的战略预计将大大有助于全球努力控制和可能根除猴痘。这项研究可以作为尼日利亚和国际公共卫生当局的基础研究，告知政策和运营决策，以控制和消除猴痘作为公共卫生威胁。猴痘病毒在尼日利亚重现，死亡率上升。应该对其危险性进行认识计划，传输模式,和潜在的人类传播。关于缺乏治疗和疫苗的公共教育至关重要。应该执行肉类检查法律，以确保安全的动物消费。
