关键词: co-infection dengue dengue virus infection hepatitis a virus (hav) hepatits a infectious disease

来  源:   DOI:10.7759/cureus.61863   PDF(Pubmed)

Abstract:
Based on the examination of four distinct cases, this case series offers a thorough investigation of the intricate relationship between dengue fever and hepatitis A infection. Despite their distinct origins, both illnesses manifest overlapping clinical features, posing considerable diagnostic hurdles, particularly in endemic regions. The cases reveal consistent symptoms such as elevated fever, abdominal discomfort, jaundice, and irregular liver function test results, underscoring the intricate nature of an accurate diagnosis. Variations in age distribution and the severity of symptoms underscore the necessity for tailored treatment approaches. Diagnostic challenges stem from the similarity in clinical presentations and shared laboratory abnormalities, necessitating comprehensive serological assessments. Therapeutic strategies entail a multidisciplinary approach addressing both hepatic and systemic manifestations, with supportive measures ensuring favorable clinical outcomes. Despite the complexities involved, timely interventions facilitate gradual symptom amelioration and successful patient recovery. Informing clinical practice and directing public health actions, this case series provides insightful information about the diagnostic and treatment complications associated with co-occurring dengue fever and hepatitis A infection.
摘要:
根据对四个不同案件的审查,本病例系列提供了对登革热与甲型肝炎感染之间复杂关系的彻底调查。尽管它们的起源不同,两种疾病都表现出重叠的临床特征,构成相当大的诊断障碍,特别是在流行地区。这些病例表现出一致的症状,例如发烧,腹部不适,黄疸,和不规则的肝功能检查结果,强调准确诊断的复杂性。年龄分布和症状严重程度的变化强调了定制治疗方法的必要性。诊断挑战源于临床表现的相似性和共同的实验室异常,需要进行全面的血清学评估。治疗策略需要多学科方法来解决肝脏和全身表现,支持措施确保良好的临床结果。尽管涉及到复杂性,及时的干预有助于逐步改善症状和成功的患者康复。告知临床实践并指导公共卫生行动,本病例系列提供了与同时发生的登革热和甲型肝炎感染相关的诊断和治疗并发症的深刻信息.
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