PDF(Pubmed)
Abstract：
Melorheostosis is a noncancerous bone disease characterized by abnormal bone and soft tissue growth. Despite being identified almost a century ago, there are still many unknown aspects surrounding this condition. It can often be an incidental discovery, with patients experiencing associated pain and deformities. Diagnosis typically relies on X-rays, although not all cases exhibit the classic candle wax appearance. A new imaging sign known as the \"dumpling on a plate sign\" has been proposed for flat bones for both MRI and CT scans. A biopsy may be necessary in cases of uncertainty, as there is not a definitive histological feature. It is not uncommon for melorheostosis to be linked with other conditions, and a collaborative approach involving a multidisciplinary team should be considered. This condition should be considered in the differential diagnosis of sclerotic bone conditions. Management is generally aimed at symptom relief, either through conservative measures or surgical intervention.
摘要：
Melorheostosis是一种非癌性骨病，其特征是骨和软组织生长异常。尽管在近一个世纪前被发现，围绕这种情况还有许多未知的方面。这通常是偶然的发现，患者经历相关的疼痛和畸形。诊断通常依赖于X射线，虽然不是所有的情况下表现出经典的蜡烛蜡的外观。已经提出了一种新的成像标志，称为“盘子上的饺子”，用于MRI和CT扫描的扁平骨骼。在不确定的情况下可能需要活检，因为没有明确的组织学特征。与其他疾病有关的melorheostopsis并不少见，应考虑采用多学科小组的协作方法。在硬化骨疾病的鉴别诊断中应考虑这种情况。管理通常旨在缓解症状，通过保守措施或手术干预。
