关键词: Brazil HIV prevention Latin America Pre-exposure prophylaxis (PrEP) Sexual and gender minorities Young MSM

来  源:   DOI:10.1016/j.lana.2024.100798   PDF(Pubmed)

Abstract:
UNASSIGNED: Young gay, bisexual, and other men who have sex with men (YMSM) in Latin America experience disproportionately high rates of HIV. While new case numbers have stabilised in other demographics, the incidence of HIV in this particular group continues to rise. We estimated the prevalence of HIV and sexually transmitted infections (STI) and identified correlates of new HIV diagnoses among YMSM in Brazil.
UNASSIGNED: Conectad@s was a respondent-driven sampling-based study to recruit and engage YMSM in HIV prevention and treatment services in Rio de Janeiro, Brazil (November 2021-October 2022). Eligibility criteria were age 18-24 years and self-identification as MSM (cis/trans) or non-binary person who have sex with men. Participants underwent HIV/STI testing and completed a socio-behavioural questionnaire. We described baseline characteristics by HIV status and used logistic regression models to identify correlates of new HIV diagnoses. Trial ID: DERR1-10.2196/34885.
UNASSIGNED: Among 409 participants, 370 (90.5%) self-identified as cisgender men, nine (2.2%) transgender men, and 30 (7.3%) non-binary. Median age was 21 years (IQR: 20-23), with 80 (19.6%) aged 18-19 years. Most self-identified as Black or Pardo (70.6%); 109 (26.7%) never tested for HIV. HIV prevalence was 9.8%; 50% (n = 20/40) were newly diagnosed with HIV. Only nine participants ever used PrEP and three were currently using it. Overall, 133 (32.5%) reported sexual violence in their lifetime and 102 (24.9%) reported a suicide attempt. Prevalence of active syphilis, chlamydia, and gonorrhoea were 14.4%, 15.9%, and 14.7%, respectively. New HIV diagnoses were positively associated with engaging in high-risk behaviour (aOR 4.88 [95% CI: 1.88-13.40]) and anxiety (aOR 2.67 [95% CI: 1.01-7.70]), and negatively associated with ever disclosing sexual orientation (aOR 0.19 [95% CI: 0.04-0.92]) and HIV knowledge (aOR 0.77 [95% CI: 0.59-1.01]).
UNASSIGNED: High prevalence of HIV coupled with a high proportion of new HIV diagnoses underscore a potentially growing HIV epidemic among YMSM in Brazil.
UNASSIGNED: National Institutes of Health (NIH), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Ministry of Health of Brazil.
摘要:
年轻的同性恋,双性恋,和拉丁美洲其他男男性行为者(YMSM)的艾滋病毒感染率过高。虽然新的病例数量在其他人口统计数据中已经稳定下来,艾滋病毒在这一特殊群体中的发病率持续上升。我们估计了艾滋病毒和性传播感染(STI)的患病率,并确定了巴西YMSM中艾滋病毒新诊断的相关性。
Conectad@s是一项由受访者驱动的基于抽样的研究,目的是在里约热内卢招募和聘用YMSM参与艾滋病毒预防和治疗服务,巴西(2021年11月-2022年10月)。资格标准为18-24岁,自我认同为MSM(顺式/反式)或非二元性男性。参与者接受了艾滋病毒/性传播感染检测,并完成了社会行为问卷。我们通过HIV状况描述了基线特征,并使用逻辑回归模型来确定新HIV诊断的相关性。试验编号:DERR1-10.2196/34885。
在409名参与者中,370人(90.5%)自我认定为顺性男性,九名(2.2%)变性人,和30(7.3%)非二进制。年龄中位数为21岁(IQR:20-23),80岁(19.6%),年龄在18-19岁。大多数人自称是黑人或帕尔多(70.6%);109人(26.7%)从未检测过艾滋病毒。HIV患病率为9.8%;新诊断为HIV的50%(n=20/40)。只有9名参与者曾经使用过PrEP,目前有3名参与者正在使用它。总的来说,133(32.5%)报告了一生中的性暴力,102(24.9%)报告了自杀未遂。活动性梅毒的患病率,衣原体,淋病占14.4%,15.9%,和14.7%,分别。新的HIV诊断与从事高风险行为(aOR4.88[95%CI:1.88-13.40])和焦虑(aOR2.67[95%CI:1.01-7.70])呈正相关,与曾经披露的性取向(aOR0.19[95%CI:0.04-0.92])和HIV知识(aOR0.77[95%CI:0.59-1.01])呈负相关。
艾滋病毒的高流行率以及新的艾滋病毒诊断的高比例突显了巴西YMSM中艾滋病毒流行的潜在增长。
美国国立卫生研究院(NIH),巴西国家卫生部。
公众号