METHODS: One hundred and forty patients with STEMI who received PCI in Putuo Hospital of Shanghai from October 2021 to September 2022 were categorized into CMD and non-CMD groups according to the caIMR value. The baseline information, patient-related examinations, and the occurrence of MACE at the 12-month follow-up were collected to investigate risk factors in patients with STEMI.
RESULTS: We divided 140 patients with STEMI enrolled into two groups according to caIMR results, including 61 patients diagnosed with CMD and 79 patients diagnosed with non-CMD. A total of 21 MACE occurred during the 1 year of follow-up. Compared with non-CMD group, patients with CMD showed a significantly higher risk of MACE. A multivariate Cox regression model was conducted for the patients, and it was found thatcaIMR was a significant predictor of prognosis in STEMI patients (HR: 8.921). Patients with CMD were divided into culprit vascular CMD and non-culprit vascular CMD, and the result found that culprit vascular CMD was associated with the incidence of MACE (OR: 4.75) and heart failure (OR: 7.50).
CONCLUSIONS: CaIMR is a strong predictor of clinical outcomes and can provide an objective risk stratification for patients with STEMI. There is a strong correlation among leukocyte index, the use of furosemide, Killips classification, and clinical outcomes.
方法:根据caIMR值将2021年10月至2022年9月在上海市普陀医院行PCI的150例STEMI患者分为CMD组和非CMD组。基线信息,与病人相关的检查,收集随访12个月时MACE的发生情况,探讨STEMI患者的危险因素。
结果:我们根据caIMR结果将140例STEMI患者分为两组,包括61例诊断为CMD的患者和79例诊断为非CMD的患者。随访1年期间共发生21次MACE。与非CMD组相比,CMD患者出现MACE的风险显著增高.对患者进行多变量Cox回归模型,发现caIMR是STEMI患者预后的重要预测因子(HR:8.921)。将CMD患者分为罪犯血管CMD和非罪犯血管CMD,结果发现,罪犯血管CMD与MACE(OR:4.75)和心力衰竭(OR:7.50)的发生率有关。
结论:CaIMR是临床结局的强预测因子,可以为STEMI患者提供客观的风险分层。白细胞指数之间有很强的相关性,使用呋塞米,Killips分类,和临床结果。