Abstract：
This study is to analyze and compare the diagnostic efficacy of the ADNEX model and O-RADS in Northeast China for benign and malignant ovarian-adnexal tumors. From July 2020 to February 2022, ultrasound images of 312 ovarian-adnexal masses included in the study were analyzed retrospectively, and the properties of these masses were identified using the ADNEX model and O-RADS. The diagnostic efficiency of the ADNEX model and O-RADS was analyzed using a ROC curve, and the capacities of the two models in differentiating benign and malignant ovarian masses at the optimum cutoff value were compared, as well as the consistency of their diagnosis results was evaluated. The study included 312 ovarian-adnexal masses, including 145 malignant masses and 167 benign masses from 287 patients with an average age of (46.8 ± 11.3) years. The AUC of the ADNEX model was 0.974, and the optimum cutoff value was the risk value > 24.2%, with the corresponding sensitivity and specificity being 97.93 and 86.83, respectively. The AUC of the O-RADS was 0.956, and the optimum cutoff value was > O-RADS 3, with the corresponding sensitivity and specificity being 97.24 and 85.03, respectively. The AUCs of the two models were 0.924 and 0.911 at the optimum cutoff values, with no statistical differences between them (P = 0.284). Consistency analysis: the kappa values of the two models for the determination and pathological results of masses were 0.840 and 0.815, respectively, and that for the diagnostic outcomes was 0.910. Both the ADNEX model and O-RADS had good diagnostic performance in people from Northeast China. Their diagnostic capabilities were similar, and diagnostic results were highly consistent at the optimum cutoff values.
摘要：
本研究旨在分析并比较中国东北地区ADNEX模型和O-RADS对良恶性卵巢附件肿瘤的诊断效能。从2020年7月至2022年2月，对纳入研究的312个卵巢附件肿块的超声图像进行回顾性分析，并使用ADNEX模型和O-RADS鉴定了这些质量的性质。使用ROC曲线分析ADNEX模型和O-RADS的诊断效率,并比较了两种模型在最佳临界值下区分良性和恶性卵巢肿块的能力，以及他们的诊断结果的一致性进行了评估。该研究包括312个卵巢附件肿块，其中恶性肿块145例,良性肿块167例,平均年龄(46.8±11.3)岁。ADNEX模型的AUC为0.974，最佳临界值为风险值>24.2%，相应的敏感性和特异性分别为97.93和86.83。O-RADS的AUC为0.956，最佳截断值为>O-RADS3，相应的敏感性和特异性分别为97.24和85.03。在最佳截止值处，两个模型的AUC分别为0.924和0.911，差异无统计学意义(P=0.284)。一致性分析:两种模型对肿块的判定和病理结果的kappa值分别为0.840和0.815,诊断结果为0.910.ADNEX模型和O-RADS在中国东北地区的人群中均具有良好的诊断性能。他们的诊断能力相似，和诊断结果在最佳截止值处高度一致。
