Abstract:
Carcinoma en cuirasse (CeC) is an uncommon presentation of metastatic cutaneous carcinoma, most often originating from breast carcinoma. We present a case study of a man in his 30s exhibiting progressive skin thickening over the left chest, alongside appetite and weight loss. On examination, the patient had painless skin induration and palpable, matted, hard, immobile and non-tender axillary, cervical and inguinal lymphadenopathy. Imaging revealed metabolically active left cervical, retro pectoral, inguinal and bilateral axillary lymph nodes with muscle involvement, likely neoplastic. Histopathology demonstrated metastatic carcinoma, morphologically originating from the breast. CeC most often presents after therapy, but our case reveals that it may be a presenting sign of an occult malignancy. CeC should be differentiated from non-oncological causes of skin thickening. Detailed history, physical examination and appropriate radiological investigations are essential. Although rare in young individuals, neoplastic aetiology should be considered if the history and physical examination suggest it.
摘要:
大肠癌(CeC)是转移性皮肤癌的罕见表现,最常起源于乳腺癌。我们提供了一个案例研究,一个30多岁的男人在左胸部表现出进行性皮肤增厚,除了食欲和减肥。在检查中,患者有无痛性皮肤硬结和明显的,杂乱的,硬,不动和不嫩的腋窝,颈部和腹股沟淋巴结肿大。影像学显示左颈椎代谢活跃,复古胸肌,腹股沟和双侧腋窝淋巴结有肌肉受累,很可能是肿瘤.组织病理学显示转移性癌,形态起源于乳房。CeC最常见于治疗后,但是我们的案例表明,这可能是一种隐匿性恶性肿瘤的表现。CeC应与皮肤增厚的非肿瘤原因区分开。详细的历史,体格检查和适当的放射学检查至关重要。虽然在年轻人中很少见,如果病史和体格检查表明,应考虑肿瘤的病因。