Abstract：
UNASSIGNED: To comprehensively assess the dose-response association between dietary glycemic index (GI) and glycemic load (GL) and gestational diabetes mellitus (GDM) risk.
UNASSIGNED: PubMed, Embase, Cochrane Library, Web of Science, CNKI, WanFang, and VIP databases were searched up to May 29, 2024. Studies with at least three exposure categories were included. Dose-response analysis was also performed when covariates were adjusted in the included studies.
UNASSIGNED: Thirteen studies involving 39,720 pregnant women were included. A linear relationship was found between GI and the risk of GDM (χ2 = 4.77, Pnon-linearity = .0923). However, association was not significant (χ2 = 0.06, p = .8000). For every unit increase in GI (range 0-30), GDM risk increased by 0.29%. After adjusting for covariates, the linear relationship persisted (χ2 = 4.95, Pnon-linearity = .084) with no significant association (χ2 = 0.08, p = .7775). For GL, a linear relationship was also found (χ2 = 4.17, Pnon-linearity =.1245), but GL was not significantly associated with GDM risk (χ2 = 2.63, p = .1049). The risk of GDM increased by 0.63% per unit increase in GL. After covariate adjustment, a significant association was observed (χ2 = 6.28, p = .0122).
UNASSIGNED: No significant association between GI and GDM risk was found. After adjusting for covariates, GL shows a significant association with GDM risk. Our findings emphasize the importance of considering dietary GL in managing the risk of GDM. Future research should continue to explore these relationships with standardized diagnostic criteria and robust adjustment for potential confounders.
UNASSIGNED: PubMed, Embase, Cochrane Library, Web of Science, CNKI, WanFang, and VIP databases were searched up to May 29, 2024. Studies with at least three exposure categories were included. Dose-response analysis was also performed when covariates were adjusted in the included studies.
UNASSIGNED: Thirteen studies involving 39,720 pregnant women were included. A linear relationship was found between GI and the risk of GDM (χ2 = 4.77, Pnon-linearity = .0923). However, association was not significant (χ2 = 0.06, p = .8000). For every unit increase in GI (range 0-30), GDM risk increased by 0.29%. After adjusting for covariates, the linear relationship persisted (χ2 = 4.95, Pnon-linearity = .084) with no significant association (χ2 = 0.08, p = .7775). For GL, a linear relationship was also found (χ2 = 4.17, Pnon-linearity =.1245), but GL was not significantly associated with GDM risk (χ2 = 2.63, p = .1049). The risk of GDM increased by 0.63% per unit increase in GL. After covariate adjustment, a significant association was observed (χ2 = 6.28, p = .0122).
UNASSIGNED: No significant association between GI and GDM risk was found. After adjusting for covariates, GL shows a significant association with GDM risk. Our findings emphasize the importance of considering dietary GL in managing the risk of GDM. Future research should continue to explore these relationships with standardized diagnostic criteria and robust adjustment for potential confounders.
摘要：
■全面评估饮食血糖指数（GI）和血糖负荷（GL）与妊娠期糖尿病（GDM）风险之间的剂量反应关系。
■PubMed,Embase,科克伦图书馆,WebofScience,CNKI,万方,和VIP数据库被搜索到2024年5月29日。包括至少三个暴露类别的研究。当在纳入的研究中调整协变量时，还进行了剂量反应分析。
■纳入了13项研究，涉及39,720名孕妇。发现GI与GDM风险之间存在线性关系（χ2=4.77，P非线性=.0923）。然而,相关性不显著(χ2=0.06,p=.8000)。对于每增加一个单位的GI（范围0-30），GDM风险增加0.29%。在调整协变量后，线性关系持续(χ2=4.95,P非线性=0.084),但无显著相关性(χ2=0.08,p=0.7775).对于GL，还发现了线性关系(χ2=4.17，P非线性=.1245)，但GL与GDM风险无显著相关性(χ2=2.63,p=.1049)。GL每增加一个单位，GDM的风险增加0.63%。在协变量调整后，观察到显著关联(χ2=6.28,p=.0122).
■未发现GI和GDM风险之间存在显著关联。在调整协变量后，GL显示与GDM风险显著相关。我们的发现强调了在管理GDM风险中考虑饮食GL的重要性。未来的研究应继续探索这些关系与标准化的诊断标准和对潜在混杂因素的稳健调整。
■PubMed,Embase,科克伦图书馆,WebofScience,CNKI,万方,和VIP数据库被搜索到2024年5月29日。包括至少三个暴露类别的研究。当在纳入的研究中调整协变量时，还进行了剂量反应分析。
■纳入了13项研究，涉及39,720名孕妇。发现GI与GDM风险之间存在线性关系（χ2=4.77，P非线性=.0923）。然而,相关性不显著(χ2=0.06,p=.8000)。对于每增加一个单位的GI（范围0-30），GDM风险增加0.29%。在调整协变量后，线性关系持续(χ2=4.95,P非线性=0.084),但无显著相关性(χ2=0.08,p=0.7775).对于GL，还发现了线性关系(χ2=4.17，P非线性=.1245)，但GL与GDM风险无显著相关性(χ2=2.63,p=.1049)。GL每增加一个单位，GDM的风险增加0.63%。在协变量调整后，观察到显著关联(χ2=6.28,p=.0122).
■未发现GI和GDM风险之间存在显著关联。在调整协变量后，GL显示与GDM风险显著相关。我们的发现强调了在管理GDM风险中考虑饮食GL的重要性。未来的研究应继续探索这些关系与标准化的诊断标准和对潜在混杂因素的稳健调整。
