PDF(Pubmed)
Abstract：
Chimeric antigen receptor T cell (CAR-T) therapy is an immunotherapy that involves genetically modifying the patient\'s own T cells to express a chimeric antigen receptor, enabling them to recognize and destroy cancer cells. This treatment has revolutionized the prognosis and management of hematological malignancies, leading to a significant increase in long-term survivors. However, there is limited evidence regarding late sequelae and post-treatment care due to the recent emergence of this therapy. The rapid advancement of CAR-T therapies has created opportunities for advanced practice nurses to play a crucial role in coordinating care, providing education, and ensuring the ongoing well-being of survivors. This article provides an overview of the physical, psychosocial, and financial challenges faced by long-term survivors of CAR-T therapy and proposes a comprehensive nursing care plan to address these issues.
摘要：
嵌合抗原受体T细胞（CAR-T）疗法是一种免疫疗法，涉及遗传修饰患者自身的T细胞以表达嵌合抗原受体，使他们能够识别并摧毁癌细胞。这种治疗彻底改变了血液系统恶性肿瘤的预后和管理，导致长期幸存者的显着增加。然而,由于最近出现了这种疗法,关于晚期后遗症和治疗后护理的证据有限.CAR-T疗法的快速发展为高级执业护士创造了机会，在协调护理方面发挥关键作用。提供教育，并确保幸存者的持续福祉。本文概述了物理，社会心理,以及CAR-T治疗的长期幸存者所面临的财务挑战，并提出了一项全面的护理计划来解决这些问题。
