PDF(Pubmed)
Abstract：
Friedreich\'s ataxia (FRDA), a rare inherited neurodegenerative disease, presents distinctive complexities in obstetrical anesthesia. Available research about FRDA in obstetrics is extremely limited. In this report, the anesthetic management of a 40-year-old primigravida with FRDA undergoing cesarean delivery is presented. An uneventful cesarean delivery with effective epidural anesthesia with ropivacaine at the L2-L3 intervertebral space was performed in our case. Neither hypotension nor bradycardia was observed, and vital signs remained stable, with no need for administration of vasoactive drugs. After discharge, the parturient reported no change in her neurologic symptoms. Conclusive recommendations are contingent upon more extensive studies. Overall management and the choice to proceed with neuraxial anesthesia in a woman with FRDA should be based on comprehensive consultations in both cardio-obstetrics and pre-anesthetic evaluations.
摘要：
Friedreich的共济失调（FRDA），一种罕见的遗传性神经退行性疾病，在产科麻醉中表现出独特的复杂性。关于FRDA在产科中的可用研究非常有限。在这份报告中,介绍了40岁接受FRDA剖宫产的primigravida的麻醉管理。在我们的病例中，在L2-L3椎间隙用罗哌卡因进行了有效的硬膜外麻醉，进行了顺利的剖宫产。未观察到低血压或心动过缓，生命体征保持稳定，无需服用血管活性药物。放电后,产妇报告她的神经症状没有变化。结论性建议取决于更广泛的研究。对于FRDA的女性，总体管理和选择进行神经轴麻醉应基于心血管产科和麻醉前评估的全面咨询。
