关键词: Bibliometric study Cancer Single cell sequence Visualization

来  源:   DOI:10.1016/j.heliyon.2024.e32847   PDF(Pubmed)

Abstract:
UNASSIGNED: Exploring the different molecular and clinicopathological features of nodal cancer based on single cell sequencing can reveal the intertumoral heterogeneity in cancer, and provide new ideas for early diagnosis, treatment and prognosis analysis of cancer.
UNASSIGNED: The hotspots, the features of worldwide scientific output, and the frontiers concerning single cell sequence related to cancer from 2011 to 2024 were determined using our bibliometric analysis. Web of Science Core Collection (WOSCC) database was searched for publications on single cell sequence associated with cancer that were published between 2011 and 2024. According to the journals, keywords, number of records, affiliations, citations, and countries, we conducted a bibliometric analysis. With the use of the data gathered from the WOSCC, geographic distribution was visualized, keyword, affiliation, and author cluster analyses were conducted, and co-cited references were reviewed and a descriptive analysis was also performed.
UNASSIGNED: From the analysis, it was concluded that 6189 articles that were published between 2011 and 2024 in total were identified. Frontiers in immunology is the leading journal with the most publications in field of the research. The five clusters that were identified for hotspots included immunotherapy, single-cell RNA sequencing, hepatocellular carcinoma, proliferation, gene expression appeared the most frequently. Journals, nations, organizations, scholars with most contribution and most referenced publications globally were extracted. Studies have mostly concentrated on the spatial transcriptomics, pan-cancer analysis, hepatocellular carcinoma et al.
UNASSIGNED: Single-cell sequencing plays a significant role in tumor diagnosis, treatment and prognosis.
摘要:
基于单细胞测序探索淋巴结癌的不同分子和临床病理特征可以揭示癌症的肿瘤间异质性,为早期诊断提供新思路,癌症的治疗和预后分析。
热点,全球科学产出的特点,并使用我们的文献计量分析确定了2011年至2024年与癌症相关的单细胞序列的前沿。搜索2011年至2024年之间发表的与癌症相关的单细胞序列的WebofScienceCoreCollection(WOSCC)数据库。根据期刊,关键词,记录数,从属关系,引文,和国家,我们进行了文献计量分析。通过使用从WOSCC收集的数据,地理分布是可视化的,关键字,从属关系,并进行了作者聚类分析,和共同引用的参考文献进行了审查,并进行了描述性分析。
从分析来看,得出的结论是,共发现了2011年至2024年间发表的6189篇文章。免疫学前沿是该研究领域出版物最多的领先期刊。为热点确定的五个集群包括免疫疗法,单细胞RNA测序,肝细胞癌,扩散,基因表达最频繁。Journals,国家,组织,提取了全球贡献最大和引用最多的出版物的学者。研究主要集中在空间转录组学上,泛癌症分析,肝细胞癌等。
单细胞测序在肿瘤诊断中起着重要作用,治疗和预后。
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