关键词: Cross-sectional survey Erectile dysfunction National health and nutrition examination survey (NHANES) Physical activity Smoking

来  源:   DOI:10.1016/j.heliyon.2024.e32884   PDF(Pubmed)

Abstract:
UNASSIGNED: Physical activity-related interventions alleviate the severity of erectile dysfunction (ED), but it is unknown whether the recommended volume of physical activity (PA) or a higher level of physical activity reduces the likelihood of ED in adult males. We aimed to evaluate the association between the recommended volume of PA and ED among US male adults.
UNASSIGNED: A nationally representative cross-sectional survey.
UNASSIGNED: National Health and Nutrition Examination Survey 2001-2004.
UNASSIGNED: A total of 2509 men aged ≥20 years were enrolled.
UNASSIGNED: ED and PA were assessed by a standardised self-report questionnaire. Weighted logistic regression analysis and spline fitting were used to assess the relationship between PA volume and the odds of ED.
UNASSIGNED: Among 2509 US adult males, the mean (standard error) age was 43.7 (0.46) years. A total of 61.1 % of men reached the recommended volume of aerobic PA. Compared with participants not meeting the PA guidelines, individuals who had recommended aerobic activities demonstrated a 34 % reduction in the odds of having ED (OR 0.66, 95 % CI 0.48-0.90; p = 0.011). Notably, according to the restricted cubic spline, we revealed a dose‒response pattern between PA volume and reduced odds of ED, even when exceeding the recommended PA levels. When compared to males with moderate-equivalent PA of less than 150 min/week, the odds of ED in those with moderate-equivalent PA levels of 150-300 min/week and >300 min/week decreased by 22 % and 39 %, respectively. Compared with participants who did not meet the PA guidelines, the multivariable-adjusted ORs (95 % CIs) of ED associated with adequate PA volumes were 0.37 (0.22-0.61) among non-smokers and 0.85 (0.57-1.25) among current smokers (p for interaction = 0.023).
UNASSIGNED: Our findings supported the benefit of meeting the guideline-recommended PA equivalents or higher volumes for ED prevention. However, PA-related benefit might be significantly diminished by smoking.
摘要:
与身体活动相关的干预措施可缓解勃起功能障碍(ED)的严重程度,但尚不清楚推荐的体力活动(PA)或更高水平的体力活动是否会降低成年男性ED的可能性。我们旨在评估美国成年男性中PA的推荐量与ED之间的关联。
全国代表性的横断面调查。
2001-2004年全国健康和营养检查调查。
共纳入2509名年龄≥20岁的男性。
ED和PA通过标准化的自我报告问卷进行评估。使用加权logistic回归分析和样条拟合评估PA体积与ED几率之间的关系。
在2509名美国成年男性中,平均(标准误差)年龄为43.7(0.46)岁.共有61.1%的男性达到了推荐的有氧PA量。与不符合PA指南的参与者相比,推荐有氧活动的个体出现ED的几率降低了34%(OR0.66,95%CI0.48~0.90;p=0.011).值得注意的是,根据受限制的三次样条,我们揭示了PA体积和ED几率降低之间的剂量反应模式,即使超过建议的PA水平。与中等等值PA小于150分钟/周的男性相比,中等当量PA水平为150-300分钟/周和>300分钟/周的患者的ED几率下降了22%和39%,分别。与不符合PA指南的参与者相比,ED的多变量校正OR(95%CI)在非吸烟者中为0.37(0.22-0.61),在当前吸烟者中为0.85(0.57-1.25)(交互作用p=0.023).
我们的研究结果支持了符合指南推荐的PA当量或更高剂量预防ED的益处。然而,与PA相关的益处可能因吸烟而显著减少。
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