UNASSIGNED: A nationally representative cross-sectional survey.
UNASSIGNED: National Health and Nutrition Examination Survey 2001-2004.
UNASSIGNED: A total of 2509 men aged ≥20 years were enrolled.
UNASSIGNED: ED and PA were assessed by a standardised self-report questionnaire. Weighted logistic regression analysis and spline fitting were used to assess the relationship between PA volume and the odds of ED.
UNASSIGNED: Among 2509 US adult males, the mean (standard error) age was 43.7 (0.46) years. A total of 61.1 % of men reached the recommended volume of aerobic PA. Compared with participants not meeting the PA guidelines, individuals who had recommended aerobic activities demonstrated a 34 % reduction in the odds of having ED (OR 0.66, 95 % CI 0.48-0.90; p = 0.011). Notably, according to the restricted cubic spline, we revealed a dose‒response pattern between PA volume and reduced odds of ED, even when exceeding the recommended PA levels. When compared to males with moderate-equivalent PA of less than 150 min/week, the odds of ED in those with moderate-equivalent PA levels of 150-300 min/week and >300 min/week decreased by 22 % and 39 %, respectively. Compared with participants who did not meet the PA guidelines, the multivariable-adjusted ORs (95 % CIs) of ED associated with adequate PA volumes were 0.37 (0.22-0.61) among non-smokers and 0.85 (0.57-1.25) among current smokers (p for interaction = 0.023).
UNASSIGNED: Our findings supported the benefit of meeting the guideline-recommended PA equivalents or higher volumes for ED prevention. However, PA-related benefit might be significantly diminished by smoking.
■全国代表性的横断面调查。
■2001-2004年全国健康和营养检查调查。
■共纳入2509名年龄≥20岁的男性。
■ED和PA通过标准化的自我报告问卷进行评估。使用加权logistic回归分析和样条拟合评估PA体积与ED几率之间的关系。
■在2509名美国成年男性中,平均(标准误差)年龄为43.7(0.46)岁.共有61.1%的男性达到了推荐的有氧PA量。与不符合PA指南的参与者相比,推荐有氧活动的个体出现ED的几率降低了34%(OR0.66,95%CI0.48~0.90;p=0.011).值得注意的是,根据受限制的三次样条,我们揭示了PA体积和ED几率降低之间的剂量反应模式,即使超过建议的PA水平。与中等等值PA小于150分钟/周的男性相比,中等当量PA水平为150-300分钟/周和>300分钟/周的患者的ED几率下降了22%和39%,分别。与不符合PA指南的参与者相比,ED的多变量校正OR(95%CI)在非吸烟者中为0.37(0.22-0.61),在当前吸烟者中为0.85(0.57-1.25)(交互作用p=0.023).
■我们的研究结果支持了符合指南推荐的PA当量或更高剂量预防ED的益处。然而,与PA相关的益处可能因吸烟而显著减少。