PDF(Pubmed)
Abstract：
In Canada, Gonorrhea infection ranks as the second most prevalent sexually transmitted infection. In 2018, Manitoba reported an incidence rate three times greater than the national average. This study aims to investigate the spatial, temporal, and spatio-temporal patterns of Gonorrhea infection in Manitoba, using individual-level laboratory-confirmed administrative data provided by Manitoba Health from 2000 to 2016. Age and sex patterns indicate that females are affected by infections at younger ages compared to males. Moreover, there is an increase in repeated infections in 2016, accounting for 16% of the total infections. Spatial analysis at the 96 Manitoba regional health authority districts highlights significant positive spatial autocorrelation, demonstrating a clustered distribution of the infection. Northern districts of Manitoba and central Winnipeg were identified as significant clusters. Temporal analysis shows seasonal patterns, with higher infections in late summer and fall. Additionally, spatio-temporal analysis reveals clusters during high-risk periods, with the most likely cluster in the northern districts of Manitoba from January 2006 to June 2014, and a secondary cluster in central Winnipeg from June 2004 to November 2012. This study identifies that Gonorrhea infection transmission in Manitoba has temporal, spatial, and spatio-temporal variations. The findings provide vital insights for public health and Manitoba Health by revealing high-risk clusters and emphasizing the need for focused and localized prevention, control measures, and resource allocation.
摘要：
在加拿大,淋病感染是第二大最普遍的性传播感染。2018年，马尼托巴省报告的发病率是全国平均水平的三倍。本研究旨在探讨空间,temporal,曼尼托巴省淋病感染的时空格局，使用曼尼托巴省卫生部从2000年到2016年提供的个体层面的实验室确认的行政数据.年龄和性别模式表明，与男性相比，女性在年轻时受到感染的影响。此外，2016年重复感染病例有所增加,占总感染病例的16%。曼尼托巴96个区域卫生当局区的空间分析突出了显著的正空间自相关，显示感染的聚集分布。马尼托巴北部地区和温尼伯中部地区被确定为重要的集群。时间分析显示了季节性模式，夏末和秋季感染率较高。此外,时空分析揭示了高风险时期的集群，从2006年1月至2014年6月，最有可能的集群在曼尼托巴北部地区，从2004年6月至2012年11月，在温尼伯中部有一个次级集群。这项研究确定，淋病感染在曼尼托巴中传播有时间，空间,和时空变化。这些发现揭示了高风险集群，并强调了重点和局部预防的必要性，为公共卫生和曼尼托巴卫生提供了重要的见解。控制措施,和资源分配。
