PDF(Pubmed)
Abstract：
UNASSIGNED: This study aimed to investigate the management of vascular risk factors, with a specific focus on understanding the various factors affecting risk factor control through an in-depth analysis of clinical data and a longitudinal follow-up of patients who have experienced ischemic strokes.
UNASSIGNED: A total of 1,572 participants were included in the analysis. We assessed thresholds for blood pressure (BP), low-density lipoprotein cholesterol (LDL-C), and glycated hemoglobin (HbA1c) levels to uncover the contextual conditions and factors affecting vascular risk factor control. Moreover, the study also scrutinized medication compliance at intervals of 3, 6, and 12 months post-onset. Logistic regression was used to adjust for confounding factors.
UNASSIGNED: At 3, 6, and 12 months, BP,LDL, hemoglobin control targets were achieved in 50.7, 51.8, and 50.6%; 51.5, 59.4, and 50.6%; 48.1, 44.0, and 48.4%,respectively. Notably, age was associated with the achievement of BP control (odds ratio [OR], 0.96; 95% confidence intervals [CI], 0.94-0.98; p < 0.0001). Ethnic minorities (OR, 4.23; 95% CI, 1.19-15.09; p = 0.02) and individuals with coronary heart disease (OR, 0.5; 95% CI, 0.3-1.0; p = 0.05) experienced decreased BP control ratios. A previous history of stroke (OR, 1.7; 95% CI, 1.0-2.8; p = 0.03) and unrestricted alcohol consumption (OR, 3.3; 95% CI, 1.0-11.1; p = 0.05) was significantly associated with the achievement of lipid control. Furthermore, lifestyle modifications were significantly correlated with the achievement of BP control (OR, 0.19; 95% CI, 0.12-0.30; p < 0.01), blood glucose control (OR, 0.03; 95% CI, 0.01-0.08; p < 0.01), and blood lipid control (OR, 0.26; 95% CI, 0.16-0.42; p < 0.01). The absence of regular physical activity was associated with lower rates of glycemic (OR, 0.14; 95% CI, 0.06-0.36; p < 0.01) and lipid controls (OR, 0.55; 95% CI, 0.33-0.90; p = 0.01). Over time, overall medication compliance declined.
UNASSIGNED: Within the cohort of patients under medication, the compliance rate concerning vascular risk factors remains unsatisfactory. Attention should be paid to compliance with secondary prevention medications and enhance the control of vascular risk factors, as compliance emerges as the key to effective prevention.
UNASSIGNED: A total of 1,572 participants were included in the analysis. We assessed thresholds for blood pressure (BP), low-density lipoprotein cholesterol (LDL-C), and glycated hemoglobin (HbA1c) levels to uncover the contextual conditions and factors affecting vascular risk factor control. Moreover, the study also scrutinized medication compliance at intervals of 3, 6, and 12 months post-onset. Logistic regression was used to adjust for confounding factors.
UNASSIGNED: At 3, 6, and 12 months, BP,LDL, hemoglobin control targets were achieved in 50.7, 51.8, and 50.6%; 51.5, 59.4, and 50.6%; 48.1, 44.0, and 48.4%,respectively. Notably, age was associated with the achievement of BP control (odds ratio [OR], 0.96; 95% confidence intervals [CI], 0.94-0.98; p < 0.0001). Ethnic minorities (OR, 4.23; 95% CI, 1.19-15.09; p = 0.02) and individuals with coronary heart disease (OR, 0.5; 95% CI, 0.3-1.0; p = 0.05) experienced decreased BP control ratios. A previous history of stroke (OR, 1.7; 95% CI, 1.0-2.8; p = 0.03) and unrestricted alcohol consumption (OR, 3.3; 95% CI, 1.0-11.1; p = 0.05) was significantly associated with the achievement of lipid control. Furthermore, lifestyle modifications were significantly correlated with the achievement of BP control (OR, 0.19; 95% CI, 0.12-0.30; p < 0.01), blood glucose control (OR, 0.03; 95% CI, 0.01-0.08; p < 0.01), and blood lipid control (OR, 0.26; 95% CI, 0.16-0.42; p < 0.01). The absence of regular physical activity was associated with lower rates of glycemic (OR, 0.14; 95% CI, 0.06-0.36; p < 0.01) and lipid controls (OR, 0.55; 95% CI, 0.33-0.90; p = 0.01). Over time, overall medication compliance declined.
UNASSIGNED: Within the cohort of patients under medication, the compliance rate concerning vascular risk factors remains unsatisfactory. Attention should be paid to compliance with secondary prevention medications and enhance the control of vascular risk factors, as compliance emerges as the key to effective prevention.
摘要：
■本研究旨在探讨血管危险因素的管理，通过对临床数据的深入分析和对缺血性卒中患者的纵向随访，重点了解影响危险因素控制的各种因素。
■共有1,572名参与者被纳入分析。我们评估了血压（BP）的阈值，低密度脂蛋白胆固醇（LDL-C），和糖化血红蛋白（HbA1c）水平，以揭示影响血管危险因素控制的背景条件和因素。此外，该研究还在发病后3个月,6个月和12个月的时间间隔对药物依从性进行了审查.Logistic回归用于校正混杂因素。
■在3、6和12个月时，BP,LDL,血红蛋白控制目标分别为50.7、51.8和50.6%；51.5、59.4和50.6%；48.1、44.0和48.4%，分别。值得注意的是,年龄与血压控制的实现相关(比值比[OR]，0.96；95%置信区间[CI]，0.94-0.98；p<0.0001）。少数民族（或，4.23；95%CI，1.19-15.09；p=0.02）和冠心病患者（OR，0.5；95%CI，0.3-1.0；p=0.05）血压控制率下降。以前的中风史（或，1.7；95%CI，1.0-2.8；p=0.03）和不受限制的饮酒（OR，3.3；95％CI，1.0-11.1；p=0.05）与脂质控制的实现显着相关。此外，生活方式的改变与血压控制的实现显着相关(OR，0.19；95%CI，0.12-0.30；p<0.01），血糖控制（OR，0.03；95%CI，0.01-0.08；p<0.01），和血脂控制(OR，0.26；95%CI，0.16-0.42；p<0.01)。缺乏规律的体力活动与较低的血糖率相关(OR，0.14；95%CI，0.06-0.36；p<0.01）和脂质对照（OR，0.55；95%CI，0.33-0.90；p=0.01）。随着时间的推移,总体用药依从性下降.
■在接受药物治疗的患者队列中，血管危险因素的依从率仍不能令人满意.重视二级预防用药的依从性，加强对血管危险因素的控制，随着合规成为有效预防的关键。
■共有1,572名参与者被纳入分析。我们评估了血压（BP）的阈值，低密度脂蛋白胆固醇（LDL-C），和糖化血红蛋白（HbA1c）水平，以揭示影响血管危险因素控制的背景条件和因素。此外，该研究还在发病后3个月,6个月和12个月的时间间隔对药物依从性进行了审查.Logistic回归用于校正混杂因素。
■在3、6和12个月时，BP,LDL,血红蛋白控制目标分别为50.7、51.8和50.6%；51.5、59.4和50.6%；48.1、44.0和48.4%，分别。值得注意的是,年龄与血压控制的实现相关(比值比[OR]，0.96；95%置信区间[CI]，0.94-0.98；p<0.0001）。少数民族（或，4.23；95%CI，1.19-15.09；p=0.02）和冠心病患者（OR，0.5；95%CI，0.3-1.0；p=0.05）血压控制率下降。以前的中风史（或，1.7；95%CI，1.0-2.8；p=0.03）和不受限制的饮酒（OR，3.3；95％CI，1.0-11.1；p=0.05）与脂质控制的实现显着相关。此外，生活方式的改变与血压控制的实现显着相关(OR，0.19；95%CI，0.12-0.30；p<0.01），血糖控制（OR，0.03；95%CI，0.01-0.08；p<0.01），和血脂控制(OR，0.26；95%CI，0.16-0.42；p<0.01)。缺乏规律的体力活动与较低的血糖率相关(OR，0.14；95%CI，0.06-0.36；p<0.01）和脂质对照（OR，0.55；95%CI，0.33-0.90；p=0.01）。随着时间的推移,总体用药依从性下降.
■在接受药物治疗的患者队列中，血管危险因素的依从率仍不能令人满意.重视二级预防用药的依从性，加强对血管危险因素的控制，随着合规成为有效预防的关键。
