PDF(Pubmed)
Abstract：
Introduction Benign paroxysmal positional vertigo (BPPV) is the peripheral vestibular dysfunction that most affects people worldwide, but its etiopathogenesis is still not fully understood. Considering the etiological diversity, some studies highlight the association between BPPV and thyroid diseases. Objective To investigate the association between thyroid diseases and BPPV. Data Synthesis Systematic review and meta-analysis of epidemiological studies searched in the PubMed, Web of Science, Embase, Cochrane Library, and Scopus databases. Studies that were fully available and investigated the association between BPPV and thyroid diseases were selected. The articles that composed the meta-analysis were analyzed using the dichotomous model, the Mantel-Haenszel statistical test, odds ratio (OR), and a 95% confidence interval (CI). Of the 67 articles retrieved from the databases, 7 met the eligibility criteria of the systematic review, and 4 had data necessary to perform the meta-analysis. Qualitative analysis revealed that the studies were conducted in the European and Asian continents. The predominant methodological design was the case-control type, and thyroid dysfunctions, hypothyroidism, and Hashimoto thyroiditis occurred more frequently. The meta-analysis showed no association between hypothyroidism and BPPV; however, there was a statistically significant relationship between Hashimoto thyroiditis and BPPV. Conclusion The meta-analysis results suggest a possible association between BPPV and Hashimoto thyroiditis. Nevertheless, we emphasize the need for further studies to elucidate the evidence obtained.
摘要：
简介良性阵发性位置性眩晕（BPPV）是影响全球人群的外周前庭功能障碍，但其病因仍未完全了解。考虑到病因的多样性，一些研究强调了BPPV与甲状腺疾病之间的关联.目的探讨甲状腺疾病与BPPV的关系。数据综合在PubMed中搜索的流行病学研究的系统回顾和荟萃分析，WebofScience,Embase,科克伦图书馆,和Scopus数据库。选择完全可用并调查BPPV与甲状腺疾病之间关联的研究。组成荟萃分析的文章使用二分模型进行分析，Mantel-Haenszel统计检验,比值比(OR)，和95%置信区间(CI)。在从数据库检索到的67篇文章中，7符合系统审查的资格标准，和4有必要进行荟萃分析的数据.定性分析显示，这些研究是在欧洲和亚洲大陆进行的。主要的方法设计是病例对照类型，和甲状腺功能障碍，甲状腺功能减退,桥本甲状腺炎的发生频率更高。荟萃分析显示甲状腺功能减退症和BPPV之间没有关联；然而，桥本甲状腺炎和BPPV之间有统计学上的显著关系.结论荟萃分析结果提示BPPV与桥本甲状腺炎之间可能存在关联。然而，我们强调需要进一步研究以阐明所获得的证据.
