PDF(Pubmed)
Abstract：
UNASSIGNED: Clinicians should consider spontaneous coronary artery dissection in middle-aged women presenting with acute coronary syndromes and a history of tamoxifen use, to ensure timely diagnosis, and appropriate management strategies.
UNASSIGNED: Spontaneous coronary artery dissection (SCAD) is characterized by a non-iatrogenic, nontraumatic separation of the coronary artery wall, contributing to acute coronary syndromes (ACS), and sudden cardiac death. SCAD predominantly affects the left anterior descending artery (LAD) and is frequently observed in middle-aged women. This condition has been associated with cancer treatment and exogenous hormones exposure. The diagnostic gold standard remains coronary angiography, management strategies include conservative measures, percutaneous coronary intervention (PCI), and coronary artery bypass graft surgery (CABG). We describe a case of a 54-year-old woman with breast cancer and a history of tamoxifen use, presenting with SCAD in the posterolateral branch (PLB) originating from the left circumflex artery (LCX), and right coronary artery (RCA) and managed conservatively.
UNASSIGNED: Spontaneous coronary artery dissection (SCAD) is characterized by a non-iatrogenic, nontraumatic separation of the coronary artery wall, contributing to acute coronary syndromes (ACS), and sudden cardiac death. SCAD predominantly affects the left anterior descending artery (LAD) and is frequently observed in middle-aged women. This condition has been associated with cancer treatment and exogenous hormones exposure. The diagnostic gold standard remains coronary angiography, management strategies include conservative measures, percutaneous coronary intervention (PCI), and coronary artery bypass graft surgery (CABG). We describe a case of a 54-year-old woman with breast cancer and a history of tamoxifen use, presenting with SCAD in the posterolateral branch (PLB) originating from the left circumflex artery (LCX), and right coronary artery (RCA) and managed conservatively.
摘要：
■临床医生应考虑对患有急性冠状动脉综合征和他莫昔芬使用史的中年女性进行自发性冠状动脉夹层，为了确保及时诊断，和适当的管理策略。
■自发性冠状动脉夹层（SCAD）的特征是非医源性的，冠状动脉壁的非创伤性分离，导致急性冠状动脉综合征（ACS），和心源性猝死.SCAD主要影响左前降支动脉（LAD），在中年女性中经常观察到。这种情况与癌症治疗和外源激素暴露有关。诊断的金标准仍然是冠状动脉造影,管理策略包括保守措施，经皮冠状动脉介入治疗(PCI),冠状动脉搭桥术（CABG）。我们描述了一个54岁的乳腺癌患者，有他莫昔芬使用史，在源自左回旋动脉（LCX）的后外侧支（PLB）出现SCAD，和右冠状动脉（RCA）并保守管理。
■自发性冠状动脉夹层（SCAD）的特征是非医源性的，冠状动脉壁的非创伤性分离，导致急性冠状动脉综合征（ACS），和心源性猝死.SCAD主要影响左前降支动脉（LAD），在中年女性中经常观察到。这种情况与癌症治疗和外源激素暴露有关。诊断的金标准仍然是冠状动脉造影,管理策略包括保守措施，经皮冠状动脉介入治疗(PCI),冠状动脉搭桥术（CABG）。我们描述了一个54岁的乳腺癌患者，有他莫昔芬使用史，在源自左回旋动脉（LCX）的后外侧支（PLB）出现SCAD，和右冠状动脉（RCA）并保守管理。
