PDF(Pubmed)
Abstract：
UNASSIGNED: Diabetes and hypertension are known to co-exist frequently as adverse cardiovascular risk factors. Both can produce cardiac autonomic neuropathythat can be measured by ECG RR interval-based heart rate variability (HRV). We compared 5 minutes HRV in four groups based on diabetes and hypertension.
UNASSIGNED: A cross sectional study was done on 203 participants divided into four groups- diabetics, hypertensives, diabetic-hypertensives and normotensive-nondiabetics. They were evaluated for current disease control and five minutes HRV was done in supine condition following standard protocols by Variowin HR Software. HRV parameters of time domain, frequency domain and Poincare plot were compared between groups and associated with gender, glycaemic control and blood pressure control. Statistical significance was set at p<0.05.
UNASSIGNED: Three diseasedgroups had mean age in mid-fifties, mean duration of disease > 6 years, comparable BMI, poor glycaemic and blood pressure control. As compared to normal groups, three diseased groups exhibit reduced HRV with respect to all three domains of HRV with varying statistical significance. Among diseased groups, HRV was associated with blood pressure control better than glycaemic control but not with gender. LF /HF ratio was the most consistent HRV parameter showing statistical significance in tests.
UNASSIGNED: HRV is reduced in both diabetics more than hypertensives; related to blood pressure control more than glycaemic control. It points altered cardiac autonomic balance, and possibility of cardiovascular risk and early detection of it with timely intervention. It also calls for investigation of same for reinforcement of our observations and further exploration.
UNASSIGNED: A cross sectional study was done on 203 participants divided into four groups- diabetics, hypertensives, diabetic-hypertensives and normotensive-nondiabetics. They were evaluated for current disease control and five minutes HRV was done in supine condition following standard protocols by Variowin HR Software. HRV parameters of time domain, frequency domain and Poincare plot were compared between groups and associated with gender, glycaemic control and blood pressure control. Statistical significance was set at p<0.05.
UNASSIGNED: Three diseasedgroups had mean age in mid-fifties, mean duration of disease > 6 years, comparable BMI, poor glycaemic and blood pressure control. As compared to normal groups, three diseased groups exhibit reduced HRV with respect to all three domains of HRV with varying statistical significance. Among diseased groups, HRV was associated with blood pressure control better than glycaemic control but not with gender. LF /HF ratio was the most consistent HRV parameter showing statistical significance in tests.
UNASSIGNED: HRV is reduced in both diabetics more than hypertensives; related to blood pressure control more than glycaemic control. It points altered cardiac autonomic balance, and possibility of cardiovascular risk and early detection of it with timely intervention. It also calls for investigation of same for reinforcement of our observations and further exploration.
摘要：
■已知糖尿病和高血压经常作为不良心血管危险因素共存。两者都可以产生心脏自主神经病变，可以通过基于ECGRR间隔的心率变异性（HRV）来测量。我们根据糖尿病和高血压比较了四组的5分钟HRV。
■对203名参与者进行了横断面研究，分为四组-糖尿病患者，高血压患者,糖尿病-高血压和血压正常-非糖尿病患者。根据VariowinHRSoftware的标准方案，在仰卧条件下对他们进行了5分钟的HRV评估。HRV时域参数,组间比较频域和Poincare图，并与性别相关，血糖控制和血压控制。统计学显著性设定为p<0.05。
■三个患病组的平均年龄在50多岁，平均病程>6年，可比较的BMI，血糖和血压控制不佳。与正常组相比，三个患病组相对于HRV的所有三个域表现出降低的HRV,具有不同的统计显著性。在患病群体中，HRV与血压控制比血糖控制更好，但与性别无关。LF/HF比率是在测试中显示统计学显著性的最一致的HRV参数。
■与高血压患者相比，两种糖尿病患者的HRV降低更多；与血压控制相比，与血糖控制有关。它指出心脏自主神经平衡改变，以及心血管风险的可能性，并通过及时干预早期发现。它还要求对其进行调查，以加强我们的观察和进一步的探索。
■对203名参与者进行了横断面研究，分为四组-糖尿病患者，高血压患者,糖尿病-高血压和血压正常-非糖尿病患者。根据VariowinHRSoftware的标准方案，在仰卧条件下对他们进行了5分钟的HRV评估。HRV时域参数,组间比较频域和Poincare图，并与性别相关，血糖控制和血压控制。统计学显著性设定为p<0.05。
■三个患病组的平均年龄在50多岁，平均病程>6年，可比较的BMI，血糖和血压控制不佳。与正常组相比，三个患病组相对于HRV的所有三个域表现出降低的HRV,具有不同的统计显著性。在患病群体中，HRV与血压控制比血糖控制更好，但与性别无关。LF/HF比率是在测试中显示统计学显著性的最一致的HRV参数。
■与高血压患者相比，两种糖尿病患者的HRV降低更多；与血压控制相比，与血糖控制有关。它指出心脏自主神经平衡改变，以及心血管风险的可能性，并通过及时干预早期发现。它还要求对其进行调查，以加强我们的观察和进一步的探索。
